Title |
Methods and matrices: approaches to identifying miRNAs for Nasopharyngeal carcinoma
|
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Published in |
Journal of Translational Medicine, January 2014
|
DOI | 10.1186/1479-5876-12-3 |
Pubmed ID | |
Authors |
Jordan L Plieskatt, Gabriel Rinaldi, Yanjung Feng, Paul H Levine, Samantha Easley, Elizabeth Martinez, Salman Hashmi, Nader Sadeghi, Paul J Brindley, Jeffrey M Bethony, Jason P Mulvenna |
Abstract |
Nasopharyngeal carcinoma (NPC) is a solid tumor of the head and neck. Multimodal therapy is highly effective when NPC is detected early. However, due to the location of the tumor and the absence of clinical signs, early detection is difficult, making a biomarker for the early detection of NPC a priority. The dysregulation of small non-coding RNAs (miRNAs) during carcinogenesis is the focus of much current biomarker research. Herein, we examine several miRNA discovery methods using two sample matrices to identify circulating miRNAs (c-miRNAs) associated with NPC. |
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Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 6 | 12% |
Student > Master | 6 | 12% |
Student > Bachelor | 5 | 10% |
Other | 7 | 14% |
Unknown | 7 | 14% |
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Other | 5 | 10% |
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