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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200
|
|---|---|
| Published in |
Journal of Translational Medicine, January 2014
|
| DOI | 10.1186/1479-5876-12-4 |
| Pubmed ID | |
| Authors |
Miharu Kobayashi, Carlos Salomon, Jorge Tapia, Sebastian E Illanes, Murray D Mitchell, Gregory E Rice |
| Abstract |
The role of exosomes in the pathogenesis and metastatic spread of cancer remains to be fully elucidated. Recent studies support the hypothesis that the release of exosomes from cells modifies local extracellular conditions to promote cell growth and neovascularisation. In addition, exosomes may modify the phenotype of parent and/or target cell. For example, sequestration of signaling mediators into exosomes may reduce their intracellular bioavailability to the parent cell thereby altering cell phenotype and metastatic potential. The fusion of released exosomes with target cell and delivery may also modify cell function and activity. In this study, to further elucidate the role of exosomes in ovarian cancer, the release of exosomes from two ovarian cancer cell lines of different invasive capacity and their miRNA content of exosomes were compared. The hypothesis to be tested was that ovarian cancer cell invasiveness is associated with altered release of exosomes and discordant exosomal sequestration of miRNA. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Argentina | 1 | 25% |
| Australia | 1 | 25% |
| Canada | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 50% |
| Members of the public | 2 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 181 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 2 | 1% |
| United States | 2 | 1% |
| Unknown | 177 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 44 | 24% |
| Student > Ph. D. Student | 37 | 20% |
| Other | 30 | 17% |
| Student > Doctoral Student | 12 | 7% |
| Student > Master | 12 | 7% |
| Other | 31 | 17% |
| Unknown | 15 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 78 | 43% |
| Biochemistry, Genetics and Molecular Biology | 30 | 17% |
| Medicine and Dentistry | 25 | 14% |
| Engineering | 7 | 4% |
| Chemistry | 6 | 3% |
| Other | 13 | 7% |
| Unknown | 22 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 May 2020.
All research outputs
#3,224,146
of 22,738,543 outputs
Outputs from Journal of Translational Medicine
#544
of 3,975 outputs
Outputs of similar age
#39,734
of 304,804 outputs
Outputs of similar age from Journal of Translational Medicine
#20
of 114 outputs
Altmetric has tracked 22,738,543 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,975 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 304,804 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.