Title |
Real-world effectiveness of abatacept for rheumatoid arthritis treatment in European and Canadian populations: a 6-month interim analysis of the 2-year, observational, prospective ACTION study
|
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Published in |
BMC Musculoskeletal Disorders, January 2014
|
DOI | 10.1186/1471-2474-15-14 |
Pubmed ID | |
Authors |
Hubert G Nüßlein, Rieke Alten, Mauro Galeazzi, Hanns-Martin Lorenz, Dimitrios Boumpas, Michael T Nurmohamed, William G Bensen, Gerd R Burmester, Hans-Hartmut Peter, Franz Rainer, Karel Pavelka, Melanie Chartier, Coralie Poncet, Christiane Rauch, Manuela Le Bars |
Abstract |
Discontinuation of rheumatoid arthritis (RA) treatment for lack or loss of initial response, tolerability issues, or development of antibodies against the therapeutic agent remains a challenge in clinical practice. Here we present a 6-month interim analysis of a 2-year prospective observational trial in Europe and Canada aiming to assess the real-world effectiveness, safety, and tolerability of intravenous abatacept for the treatment of moderate-to-severe RA. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Spain | 1 | 1% |
Colombia | 1 | 1% |
Unknown | 85 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 13 | 15% |
Student > Master | 13 | 15% |
Student > Ph. D. Student | 12 | 14% |
Student > Doctoral Student | 7 | 8% |
Student > Bachelor | 7 | 8% |
Other | 22 | 25% |
Unknown | 14 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 39 | 44% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 9% |
Social Sciences | 5 | 6% |
Biochemistry, Genetics and Molecular Biology | 4 | 5% |
Nursing and Health Professions | 3 | 3% |
Other | 8 | 9% |
Unknown | 21 | 24% |