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Binding of longer Aβ to transmembrane domain 1 of presenilin 1 impacts on Aβ42 generation

Overview of attention for article published in Molecular Neurodegeneration, January 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Average Attention Score compared to outputs of the same age and source

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2 X users
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1 patent

Citations

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21 Dimensions

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28 Mendeley
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Title
Binding of longer Aβ to transmembrane domain 1 of presenilin 1 impacts on Aβ42 generation
Published in
Molecular Neurodegeneration, January 2014
DOI 10.1186/1750-1326-9-7
Pubmed ID
Authors

Yu Ohki, Naoaki Shimada, Aya Tominaga, Satoko Osawa, Takuya Higo, Satoshi Yokoshima, Tohru Fukuyama, Taisuke Tomita, Takeshi Iwatsubo

Abstract

Amyloid-β peptide ending at 42nd residue (Aβ42) is believed as a pathogenic peptide for Alzheimer disease. Although γ-secretase is a responsible protease to generate Aβ through a processive cleavage, the proteolytic mechanism of γ-secretase at molecular level is poorly understood.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
United States 1 4%
Unknown 26 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 29%
Student > Ph. D. Student 3 11%
Student > Postgraduate 3 11%
Student > Master 3 11%
Student > Bachelor 2 7%
Other 6 21%
Unknown 3 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 25%
Biochemistry, Genetics and Molecular Biology 6 21%
Neuroscience 3 11%
Medicine and Dentistry 2 7%
Nursing and Health Professions 1 4%
Other 2 7%
Unknown 7 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2018.
All research outputs
#6,400,722
of 22,739,983 outputs
Outputs from Molecular Neurodegeneration
#567
of 845 outputs
Outputs of similar age
#76,282
of 306,020 outputs
Outputs of similar age from Molecular Neurodegeneration
#8
of 17 outputs
Altmetric has tracked 22,739,983 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 845 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.1. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,020 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.