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IL28B and IL10R −1087 polymorphisms are protective for chronic genotype 1 HCV infection and predictors of response to interferon-based therapy in an East-Central European cohort

Overview of attention for article published in BMC Research Notes, January 2014
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Title
IL28B and IL10R −1087 polymorphisms are protective for chronic genotype 1 HCV infection and predictors of response to interferon-based therapy in an East-Central European cohort
Published in
BMC Research Notes, January 2014
DOI 10.1186/1756-0500-7-12
Pubmed ID
Authors

Alajos Pár, Gabriella Pár, István Tornai, Ferenc Szalay, Dalma Várszegi, Edit Fráter, Mária Papp, Gabriella Lengyel, János Fehér, Márta Varga, Judit Gervain, János Schuller, Zsuzsanna Nemes, Zoltán Péterfi, Anna Tusnádi, Béla Hunyady, Attila Haragh, Zsolt Szinku, Áron Vincze, László Szereday, Péter Kisfali, Béla Melegh

Abstract

Previous studies have shown that single nucleotide polymorphisms (SNP) in IL28B and IL10R are associated with sustained virological response (SVR) in chronic hepatitis C patients treated with pegilated interferon plus ribavirin (P/R). The present study extends our earlier investigations on a large East-Central European cohort. The allele frequencies of IL28B and IL10R in genotype 1 HCV infection were compared with that of healthy controls for the purpose of examining the relationship between the polymorphisms and the SVR to P/R treatment.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 18%
Student > Doctoral Student 4 14%
Student > Ph. D. Student 3 11%
Professor > Associate Professor 2 7%
Researcher 2 7%
Other 4 14%
Unknown 8 29%
Readers by discipline Count As %
Medicine and Dentistry 12 43%
Agricultural and Biological Sciences 3 11%
Biochemistry, Genetics and Molecular Biology 2 7%
Arts and Humanities 1 4%
Immunology and Microbiology 1 4%
Other 1 4%
Unknown 8 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 January 2014.
All research outputs
#18,360,179
of 22,739,983 outputs
Outputs from BMC Research Notes
#3,010
of 4,260 outputs
Outputs of similar age
#228,693
of 304,743 outputs
Outputs of similar age from BMC Research Notes
#97
of 126 outputs
Altmetric has tracked 22,739,983 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,260 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 304,743 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 126 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.