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The emerging roles and therapeutic potential of exosomes in epithelial ovarian cancer

Overview of attention for article published in Molecular Cancer, May 2017
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Title
The emerging roles and therapeutic potential of exosomes in epithelial ovarian cancer
Published in
Molecular Cancer, May 2017
DOI 10.1186/s12943-017-0659-y
Pubmed ID
Authors

Xiaoduan Li, Xipeng Wang

Abstract

Ovarian cancer (OC) is one of the three types of malignant tumors in the female reproductive system, and epithelial ovarian cancer (EOC) is its most typical form. Due to the asymptomatic nature of the early stages and resistance to chemotherapy, EOC has both a poor prognosis and a high fatality rate. Current treatments for OC are very limited, and the 5-years survival rate is approximately 30%. Exosomes, which are microvesicles ranging from approximately 30-100 nm in size that are secreted by living cells, can be produced from different cell types and detected in various body fluids. Cancer cells can secrete more exosomes than healthy cells, and more importantly, the content of cancer cell-derived exosomes is distinct. The exosomes shedding from tumor cells are considered to be involved in tumor progression and metastasis. As such, exosomes are expected to be potential tools for tumor diagnosis and treatment. In this review, we briefly present the emerging roles of exosomes in OC and summarize related articles about their roles as diagnostic or prognostic biomarkers and in the treatment and drug resistance of OC.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 104 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 28%
Researcher 14 13%
Student > Master 12 12%
Student > Doctoral Student 6 6%
Student > Bachelor 5 5%
Other 14 13%
Unknown 24 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 32 31%
Medicine and Dentistry 15 14%
Agricultural and Biological Sciences 13 13%
Engineering 6 6%
Pharmacology, Toxicology and Pharmaceutical Science 5 5%
Other 3 3%
Unknown 30 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2021.
All research outputs
#18,968,537
of 23,511,526 outputs
Outputs from Molecular Cancer
#1,350
of 1,779 outputs
Outputs of similar age
#237,763
of 311,069 outputs
Outputs of similar age from Molecular Cancer
#24
of 34 outputs
Altmetric has tracked 23,511,526 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,779 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,069 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.