Title |
Differential proteomic analysis of synovial fluid from rheumatoid arthritis and osteoarthritis patients
|
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Published in |
Clinical Proteomics, January 2014
|
DOI | 10.1186/1559-0275-11-1 |
Pubmed ID | |
Authors |
Lavanya Balakrishnan, Mitali Bhattacharjee, Sartaj Ahmad, Raja Sekhar Nirujogi, Santosh Renuse, Yashwanth Subbannayya, Arivusudar Marimuthu, Srinivas M Srikanth, Rajesh Raju, Mukesh Dhillon, Navjyot Kaur, Ramesh Jois, Vivek Vasudev, YL Ramachandra, Nandini A Sahasrabuddhe, TS Keshava Prasad, Sujatha Mohan, Harsha Gowda, Subramanian Shankar, Akhilesh Pandey |
Abstract |
Rheumatoid arthritis and osteoarthritis are two common musculoskeletal disorders that affect the joints. Despite high prevalence rates, etiological factors involved in these disorders remain largely unknown. Dissecting the molecular aspects of these disorders will significantly contribute to improving their diagnosis and clinical management. In order to identify proteins that are differentially expressed between these two conditions, a quantitative proteomic profiling of synovial fluid obtained from rheumatoid arthritis and osteoarthritis patients was carried out by using iTRAQ labeling followed by high resolution mass spectrometry analysis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Guinea | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Philippines | 1 | <1% |
Germany | 1 | <1% |
Unknown | 112 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 24 | 21% |
Student > Ph. D. Student | 20 | 18% |
Student > Master | 18 | 16% |
Student > Bachelor | 8 | 7% |
Student > Doctoral Student | 7 | 6% |
Other | 18 | 16% |
Unknown | 19 | 17% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 26 | 23% |
Medicine and Dentistry | 24 | 21% |
Agricultural and Biological Sciences | 15 | 13% |
Immunology and Microbiology | 5 | 4% |
Engineering | 5 | 4% |
Other | 14 | 12% |
Unknown | 25 | 22% |