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Complement inhibitors for age‐related macular degeneration

Overview of attention for article published in Cochrane database of systematic reviews, January 2014
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Citations

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Title
Complement inhibitors for age‐related macular degeneration
Published in
Cochrane database of systematic reviews, January 2014
DOI 10.1002/14651858.cd009300.pub2
Pubmed ID
Authors

Michael A Williams, Gareth J McKay, Usha Chakravarthy

Abstract

Given the relatively high prevalence of age-related macular degeneration (AMD) and the increased incidence of AMD as populations age, the results of trials of novel treatments are awaited with much anticipation. The complement cascade describes a series of proteolytic reactions occurring throughout the body that generate proteins with a variety of roles including the initiation and promotion of immune reactions against foreign materials or micro-organisms. The complement cascade is normally tightly regulated, but much evidence implicates complement overactivity in AMD and so it is a logical therapeutic target in the treatment of AMD.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 148 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Unknown 147 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 27 18%
Student > Ph. D. Student 16 11%
Researcher 14 9%
Student > Bachelor 11 7%
Student > Doctoral Student 9 6%
Other 19 13%
Unknown 52 35%
Readers by discipline Count As %
Medicine and Dentistry 39 26%
Nursing and Health Professions 14 9%
Agricultural and Biological Sciences 8 5%
Psychology 7 5%
Pharmacology, Toxicology and Pharmaceutical Science 7 5%
Other 19 13%
Unknown 54 36%