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Inflammation and the developing brain: Consequences for hippocampal neurogenesis and behavior

Overview of attention for article published in Neuroscience & Biobehavioral Reviews, March 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

news
2 news outlets
twitter
5 tweeters

Citations

dimensions_citation
67 Dimensions

Readers on

mendeley
133 Mendeley
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Title
Inflammation and the developing brain: Consequences for hippocampal neurogenesis and behavior
Published in
Neuroscience & Biobehavioral Reviews, March 2014
DOI 10.1016/j.neubiorev.2014.01.004
Pubmed ID
Authors

Holly F. Green, Yvonne M. Nolan

Abstract

While the detrimental impact of inflammation on adult hippocampal neurogenesis and associated behaviors has recently gained credence, the effects of inflammation on the developing brain is an area of research which is quickly gaining momentum, and a growing number of research articles on this topic have been published in recent years. Indeed, we now know that pro-inflammatory mediators negatively influence both hippocampal neurogenesis and neuronal cytoarchitecture during brain development. Here we present a comprehensive review of the current literature on inflammation-induced changes in hippocampal neurogenesis during early life and the consequent behavioral deficits which may ensue in later life. We also offer insights into the cellular and molecular mechanisms underlying the hippocampal-dependant behavioral changes observed in neurodevelopmental disorders, particularly in those where cognitive dysfunction plays a major role. We further consider whether early-life inflammation-induced changes in hippocampal neurogenesis may contribute to the onset of mood and cognitive deficits in later life.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 2 2%
Switzerland 1 <1%
France 1 <1%
Australia 1 <1%
Germany 1 <1%
Belgium 1 <1%
United Kingdom 1 <1%
Japan 1 <1%
United States 1 <1%
Other 0 0%
Unknown 123 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 23%
Researcher 25 19%
Student > Bachelor 16 12%
Student > Master 14 11%
Student > Postgraduate 7 5%
Other 19 14%
Unknown 21 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 32 24%
Neuroscience 25 19%
Medicine and Dentistry 19 14%
Psychology 13 10%
Biochemistry, Genetics and Molecular Biology 7 5%
Other 8 6%
Unknown 29 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 May 2020.
All research outputs
#1,424,225
of 20,832,759 outputs
Outputs from Neuroscience & Biobehavioral Reviews
#628
of 3,571 outputs
Outputs of similar age
#18,532
of 283,624 outputs
Outputs of similar age from Neuroscience & Biobehavioral Reviews
#7
of 19 outputs
Altmetric has tracked 20,832,759 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,571 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.3. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,624 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.