Chapter title |
MicroRNA Regulatory Networks as Biomarkers in Obesity: The Emerging Role.
|
---|---|
Chapter number | 18 |
Book title |
Bioinformatics in MicroRNA Research
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-7046-9_18 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7044-5, 978-1-4939-7046-9
|
Authors |
Lihua Zhang, Daniel Miller, Qiuping Yang, Bin Wu M.D., Ph.D., Bin Wu |
Editors |
Jingshan Huang, Glen M. Borchert, Dejing Dou, Jun (Luke) Huan, Wenjun Lan, Ming Tan, Bin Wu |
Abstract |
Even though it is a pandemic health problem worldwide, the pathogenesis of obesity is poorly understood. Recently, emerging studies verified that microRNAs (miRNAs) are involved in complicated metabolic processes including adipocyte differentiation, fat cell formation (adipogenesis), obesity-related insulin resistance and inflammation. Many regulatory networks have been identified in murine adipose tissue, but those in human adipose tissue are not as well known. In addition, miRNAs have been detected in circulation, and thus may be usable as diagnostic indicators. MiRNAs may play an important part in regulating metabolic functions in adipose tissues and, by extension, obesity and its associated disorders. Consequently, they may be potential candidates for therapeutic targets and biomarkers. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 6 | 33% |
Student > Ph. D. Student | 3 | 17% |
Researcher | 2 | 11% |
Student > Master | 1 | 6% |
Professor > Associate Professor | 1 | 6% |
Other | 0 | 0% |
Unknown | 5 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 6 | 33% |
Medicine and Dentistry | 5 | 28% |
Chemical Engineering | 1 | 6% |
Immunology and Microbiology | 1 | 6% |
Agricultural and Biological Sciences | 1 | 6% |
Other | 0 | 0% |
Unknown | 4 | 22% |