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Title |
Transcription factor binding sites are highly enriched within microRNA precursor sequences
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Published in |
Biology Direct, December 2011
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DOI | 10.1186/1745-6150-6-61 |
Pubmed ID | |
Authors |
Jittima Piriyapongsa, I King Jordan, Andrew B Conley, Tom Ronan, Neil R Smalheiser |
Abstract |
Transcription factors are thought to regulate the transcription of microRNA genes in a manner similar to that of protein-coding genes; that is, by binding to conventional transcription factor binding site DNA sequences located in or near promoter regions that lie upstream of the microRNA genes. However, in the course of analyzing the genomics of human microRNA genes, we noticed that annotated transcription factor binding sites commonly lie within 70- to 110-nt long microRNA small hairpin precursor sequences. |
Mendeley readers
The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 5% |
United States | 2 | 4% |
Italy | 1 | 2% |
Czechia | 1 | 2% |
Germany | 1 | 2% |
Unknown | 49 | 86% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 15 | 26% |
Student > Ph. D. Student | 14 | 25% |
Student > Master | 8 | 14% |
Other | 4 | 7% |
Student > Postgraduate | 3 | 5% |
Other | 9 | 16% |
Unknown | 4 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 30 | 53% |
Biochemistry, Genetics and Molecular Biology | 13 | 23% |
Medicine and Dentistry | 5 | 9% |
Neuroscience | 2 | 4% |
Immunology and Microbiology | 1 | 2% |
Other | 1 | 2% |
Unknown | 5 | 9% |