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Increased IL-4 mRNA expression and poly-aromatic hydrocarbon concentrations from children with asthma

Overview of attention for article published in BMC Pediatrics, January 2014
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Title
Increased IL-4 mRNA expression and poly-aromatic hydrocarbon concentrations from children with asthma
Published in
BMC Pediatrics, January 2014
DOI 10.1186/1471-2431-14-17
Pubmed ID
Authors

Nasser M Al-Daghri, Sherif Abd-Alrahman, Hossam Draz, Khalid Alkharfy, Abdul Khader Mohammed, Mario S Clerici, Majed S Alokail

Abstract

Asthma is the most common chronic childhood disease. Imbalance of cytokines released from T helper cells and environmental factors, such as exposure to poly-aromatic hydrocarbon (PAH), play pivotal roles in the pathogenesis of asthma. The aim of this study was to compare the mRNA expression patterns of Interleukin (IL)-4, interferon (IFN)-γ and Acyl Co A long chain 3 (ACSL3) in peripheral blood leukocytes of children with and without asthma. To correlate the obtained mRNA data with serum IL-4, IFN-γ and PAH levels. Further, to determine the effect of in vivo exposure to PAH on mRNA expression of IL-4, IFN-γ and ACSL3 genes in a rat model.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 1 3%
Unknown 33 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 21%
Researcher 6 18%
Professor 5 15%
Student > Master 3 9%
Student > Doctoral Student 2 6%
Other 5 15%
Unknown 6 18%
Readers by discipline Count As %
Medicine and Dentistry 10 29%
Agricultural and Biological Sciences 4 12%
Biochemistry, Genetics and Molecular Biology 3 9%
Immunology and Microbiology 3 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Other 5 15%
Unknown 7 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 October 2014.
All research outputs
#14,772,245
of 22,741,406 outputs
Outputs from BMC Pediatrics
#1,902
of 2,987 outputs
Outputs of similar age
#181,676
of 305,708 outputs
Outputs of similar age from BMC Pediatrics
#28
of 51 outputs
Altmetric has tracked 22,741,406 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,987 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,708 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.