Title |
A sheeppox outbreak in Morocco: isolation and identification of virus responsible for the new clinical form of disease
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Published in |
BMC Veterinary Research, January 2014
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DOI | 10.1186/1746-6148-10-31 |
Pubmed ID | |
Authors |
Khalil Zro, Fathiah Zakham, Marouane Melloul, Elmostafa El Fahime, Moulay Mustapha Ennaji |
Abstract |
Sheeppoxvirus (SPPV) is a member of the Capripoxvirus genus of the Poxviridae family, which causes significant economic losses in Morocco. The resurgence of the sheeppox disease during 2010 was characterized by an emergence of a classical nodular form for the first time in Morocco. However, little is known about the virus strain responsible for nodular form. In this study, thirty three sheep, from the eastern region of Morocco, clinically infected were examined and dead animals were autopsied.A rapid diagnostic assay for SPPV using different type of clinical samples would be useful for outbreak management. The aim of this work was to isolate the virus strain responsible for nodular form and we identified and compared by phylogenetic analysis the field strain with Moroccan vaccine strain targeting the thymidine kinase (TK) gene and the chemokine analogue receptor of interleukin (IL8) gene. Further, it was important to investigate and validate a real-time PCR using different clinical and post-mortem samples to manage epidemic sheeppox disease. |
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Spain | 1 | 33% |
Colombia | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
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Unknown | 52 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 17% |
Student > Ph. D. Student | 7 | 13% |
Other | 5 | 10% |
Professor | 5 | 10% |
Student > Master | 5 | 10% |
Other | 9 | 17% |
Unknown | 12 | 23% |
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Veterinary Science and Veterinary Medicine | 10 | 19% |
Agricultural and Biological Sciences | 8 | 15% |
Medicine and Dentistry | 4 | 8% |
Biochemistry, Genetics and Molecular Biology | 3 | 6% |
Immunology and Microbiology | 3 | 6% |
Other | 11 | 21% |
Unknown | 13 | 25% |