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Investigation of the association between the TCF7L2 rs7903146 (C/T) gene polymorphism and obesity in a Cameroonian population: a pilot study

Overview of attention for article published in Journal of Health, Population, & Nutrition, April 2017
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1 tweeter

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2 Dimensions

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14 Mendeley
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Title
Investigation of the association between the TCF7L2 rs7903146 (C/T) gene polymorphism and obesity in a Cameroonian population: a pilot study
Published in
Journal of Health, Population, & Nutrition, April 2017
DOI 10.1186/s41043-017-0087-z
Pubmed ID
Authors

Aurelie Nguimmo-Metsadjio, Barbara Atogho-Tiedeu, Jean Jacques Noubiap, Marie-Solange Evehe, Rosine Djokam-Dadjeu, Olivier Sontsa Donfack, Dieudonne Nanfa, Edith Pascale M. Mato, Elvis Ndonwi Ngwa, Magellan Guewo-Fokeng, Priscille Pokam-Fosso, Wilfred F. Mbacham, Jean Claude Mbanya, Eugene Sobngwi

Abstract

This study aimed at investigating the association between the rs7903146 (C/T) polymorphism of the TCF7L2 gene with obesity in a Cameroonian population. This was a case-control pilot study including 61 obese and 61 non-obese Cameroonian adults. Anthropometric indices of obesity, blood pressure, fasting blood glucose, and blood lipids were measured. The rs7903146 (C/T) polymorphism of the TCF7L2 gene was genotyped using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), and genotypes were correlated with clinical and biological parameters. The T allele was predominant in the study population with a frequency of 93%. No statistically significant difference was however observed between the genotypic (p = 0.50) and allelic frequencies (p = 0.58) of obese and non-obese subjects. Comparison of clinical and biochemical parameters of C allele carriers (CX = CC + CT) with those of TT genotype showed that there was no significant difference between the lipid profile of these two groups. The rs7903146 (C/T) polymorphism of the TCF7L2 gene might not be associated with obesity in the Cameroonian population.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 21%
Researcher 2 14%
Student > Ph. D. Student 2 14%
Other 1 7%
Librarian 1 7%
Other 2 14%
Unknown 3 21%
Readers by discipline Count As %
Medicine and Dentistry 3 21%
Biochemistry, Genetics and Molecular Biology 3 21%
Agricultural and Biological Sciences 2 14%
Psychology 1 7%
Unspecified 1 7%
Other 0 0%
Unknown 4 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 June 2017.
All research outputs
#7,002,457
of 11,275,925 outputs
Outputs from Journal of Health, Population, & Nutrition
#139
of 264 outputs
Outputs of similar age
#150,636
of 267,487 outputs
Outputs of similar age from Journal of Health, Population, & Nutrition
#3
of 5 outputs
Altmetric has tracked 11,275,925 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 264 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,487 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.