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Transcriptional Control of Lineage Differentiation in Immune Cells

Overview of attention for book
Attention for Chapter 370: Genetic and Epigenetic Control of Early Lymphocyte Development.
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Mentioned by

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2 tweeters

Citations

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3 Dimensions

Readers on

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19 Mendeley
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Chapter title
Genetic and Epigenetic Control of Early Lymphocyte Development.
Chapter number 370
Book title
Transcriptional Control of Lineage Differentiation in Immune Cells
Published in
Current topics in microbiology and immunology, May 2014
DOI 10.1007/82_2014_370
Pubmed ID
Book ISBNs
978-3-31-907394-1, 978-3-31-907395-8
Authors

Tomokatsu Ikawa

Editors

Wilfried Ellmeier, Ichiro Taniuchi

Abstract

T, B, and NK lymphocytes are generated from pluripotent hematopoietic stem cells through a successive series of lineage restriction processes. Many regulatory components, such as transcription factors, cytokines/cytokine receptors, and signal transduction molecules orchestrate cell fate specification and determination. In particular, transcription factors play a key role in regulating lineage-associated gene programs. Recent findings suggest the involvement of epigenetic factors in the maintenance of cell fate. Here, we review the early developmental events during lymphocyte lineage determination, focusing on the transcriptional networks and epigenetic regulation. Finally, we also discuss the developmental relationship between acquired and innate lymphoid cells.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Venezuela, Bolivarian Republic of 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 47%
Researcher 5 26%
Student > Bachelor 2 11%
Student > Master 2 11%
Professor > Associate Professor 1 5%
Other 0 0%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 53%
Biochemistry, Genetics and Molecular Biology 4 21%
Immunology and Microbiology 2 11%
Nursing and Health Professions 1 5%
Medicine and Dentistry 1 5%
Other 0 0%
Unknown 1 5%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2014.
All research outputs
#3,556,537
of 5,038,248 outputs
Outputs from Current topics in microbiology and immunology
#247
of 351 outputs
Outputs of similar age
#82,005
of 122,487 outputs
Outputs of similar age from Current topics in microbiology and immunology
#6
of 9 outputs
Altmetric has tracked 5,038,248 research outputs across all sources so far. This one is in the 16th percentile – i.e., 16% of other outputs scored the same or lower than it.
So far Altmetric has tracked 351 research outputs from this source. They receive a mean Attention Score of 2.2. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 122,487 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.