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A biomarker based detection and characterization of carcinomas exploiting two fundamental biophysical mechanisms in mammalian cells

Overview of attention for article published in BMC Cancer, December 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
1 news outlet
twitter
1 X user
patent
2 patents
wikipedia
17 Wikipedia pages

Citations

dimensions_citation
53 Dimensions

Readers on

mendeley
99 Mendeley
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Title
A biomarker based detection and characterization of carcinomas exploiting two fundamental biophysical mechanisms in mammalian cells
Published in
BMC Cancer, December 2013
DOI 10.1186/1471-2407-13-569
Pubmed ID
Authors

Martin Grimm, Steffen Schmitt, Peter Teriete, Thorsten Biegner, Arnulf Stenzl, Jörg Hennenlotter, Hans-Joachim Muhs, Adelheid Munz, Tatjana Nadtotschi, Klemens König, Jörg Sänger, Oliver Feyen, Heiko Hofmann, Siegmar Reinert, Johannes F Coy

Abstract

Biomarkers allowing the characterization of malignancy and therapy response of oral squamous cell carcinomas (OSCC) or other types of carcinomas are still outstanding. The biochemical suicide molecule endonuclease DNaseX (DNaseI-like 1) has been used to identify the Apo10 protein epitope that marks tumor cells with abnormal apoptosis and proliferation. The transketolase-like protein 1 (TKTL1) represents the enzymatic basis for an anaerobic glucose metabolism even in the presence of oxygen (aerobic glycolysis/Warburg effect), which is concomitant with a more malignant phenotype due to invasive growth/metastasis and resistance to radical and apoptosis inducing therapies.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Netherlands 1 1%
Germany 1 1%
Italy 1 1%
Taiwan 1 1%
Unknown 93 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 23%
Student > Bachelor 12 12%
Student > Ph. D. Student 11 11%
Student > Master 10 10%
Student > Doctoral Student 5 5%
Other 12 12%
Unknown 26 26%
Readers by discipline Count As %
Medicine and Dentistry 37 37%
Agricultural and Biological Sciences 9 9%
Biochemistry, Genetics and Molecular Biology 4 4%
Immunology and Microbiology 4 4%
Unspecified 3 3%
Other 14 14%
Unknown 28 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2023.
All research outputs
#2,010,555
of 23,377,816 outputs
Outputs from BMC Cancer
#334
of 8,461 outputs
Outputs of similar age
#23,939
of 310,256 outputs
Outputs of similar age from BMC Cancer
#4
of 108 outputs
Altmetric has tracked 23,377,816 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,461 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,256 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 108 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.