↓ Skip to main content

Preoperative exercise training for patients with non-small cell lung cancer

Overview of attention for article published in Cochrane database of systematic reviews, June 2017
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

twitter
141 tweeters
facebook
5 Facebook pages

Readers on

mendeley
10 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Preoperative exercise training for patients with non-small cell lung cancer
Published in
Cochrane database of systematic reviews, June 2017
DOI 10.1002/14651858.cd012020.pub2
Pubmed ID
Authors

Vinicius Cavalheri, Catherine Granger

Abstract

Surgical resection for early stage non-small cell lung cancer (NSCLC) offers the best chance of cure, but is associated with a risk of postoperative pulmonary complications (i.e. pneumonia (new infiltrate coupled with either fever (> 38º C) and purulent secretions, or fever and white cell count > 11,000), bronchopleural fistula, severe atelectasis that requires chest physiotherapy or bronchoscopy, and prolonged mechanical ventilation (> 48 hours)). It is currently unclear if preoperative exercise training, and the potential resultant improvement in exercise capacity, may also improve postoperative outcomes, such as the risk of developing postoperative pulmonary complications, the length of postoperative intercostal drainage, or the length of hospital stay. The primary aims of this study were to determine the effect of preoperative exercise training on postoperative outcomes, such as risk of developing a postoperative pulmonary complication, and postoperative duration of intercostal catheter use in adults scheduled to undergo lung resection for NSCLC. The secondary aims of this study were to determine the effect of preoperative exercise training on length of hospital stay, fatigue, dyspnoea, exercise capacity, lung function, and postoperative mortality. We searched CENTRAL, MEDLINE (PubMed), Embase Ovid, PEDro, and SciELO on the 28(th) of November 2016. We included randomised controlled trials (RCTs) in which study participants who were scheduled to undergo lung resection for NSCLC were allocated to receive either preoperative exercise training or no exercise training. Two review authors independently screened the studies and selected those for inclusion. We performed meta-analyses for the outcomes: risk of developing a postoperative pulmonary complication; postoperative duration of intercostal catheter; length of hospital stay; post-intervention exercise capacity (6-minute walk distance), and post-intervention forced vital capacity (FVC). Although three studies reported post-intervention forced expiratory volume in 1 second (FEV1), we did not perform meta-analysis on this outcome due to significant statistical heterogeneity (I² = 93%) across the studies. Data were not available for fatigue or dyspnoea. One study reported no in-hospital postoperative mortality in either the exercise or the non-exercise groups. We identified five RCTs involving 167 participants (mean age ranged from 54 to 72.5 years; sample size ranged from 19 to 60 participants). Overall, we found that the risk of bias in the included studies was high, and the quality of evidence for all outcomes was low. Pooled data from four studies demonstrated that preoperative exercise training reduced the risk of developing a postoperative pulmonary complication by 67% (risk ratio (RR) 0.33, 95% CI 0.17 to 0.61). The number of days patients in the exercise group needed an intercostal catheter was lower than in the non-exercise group (mean difference (MD) -3.33 days, 95% CI -5.35 to -1.30 days; two studies); postoperative length of hospital stay was also lower in the exercise group (MD -4.24 days, 95% CI -5.43 to -3.06 days; four studies). Pooled data from two studies demonstrated that compared to the non-exercise group, post-intervention 6-minute walk distance (MD 18.23 m, 95% CI 8.50 to 27.96 m), and post-intervention FVC (MD 2.97% predicted, 95% CI 1.78 to 4.16% predicted) were higher in the exercise group. Preoperative exercise training may reduce the risk of developing a postoperative pulmonary complication, the duration of intercostal catheter use, postoperative length of hospital stay, and improve both exercise capacity and FVC in people undergoing lung resection for NSCLC. The findings of this review should be interpreted with caution due to disparities between the studies, risk of bias, and small sample sizes. This review emphasises the need for larger RCTs.

Twitter Demographics

The data shown below were collected from the profiles of 141 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 20%
Unspecified 1 10%
Unknown 7 70%
Readers by discipline Count As %
Unspecified 1 10%
Psychology 1 10%
Social Sciences 1 10%
Unknown 7 70%

Attention Score in Context

This research output has an Altmetric Attention Score of 92. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 February 2019.
All research outputs
#155,196
of 12,603,047 outputs
Outputs from Cochrane database of systematic reviews
#371
of 10,375 outputs
Outputs of similar age
#7,497
of 266,145 outputs
Outputs of similar age from Cochrane database of systematic reviews
#18
of 238 outputs
Altmetric has tracked 12,603,047 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,375 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.2. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,145 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 238 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.