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GS-9219/VDC-1101 - a prodrug of the acyclic nucleotide PMEG has antitumor activity inspontaneous canine multiple myeloma

Overview of attention for article published in BMC Veterinary Research, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

news
1 news outlet
twitter
3 X users

Citations

dimensions_citation
22 Dimensions

Readers on

mendeley
91 Mendeley
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Title
GS-9219/VDC-1101 - a prodrug of the acyclic nucleotide PMEG has antitumor activity inspontaneous canine multiple myeloma
Published in
BMC Veterinary Research, January 2014
DOI 10.1186/1746-6148-10-30
Pubmed ID
Authors

Douglas H Thamm, David M Vail, Ilene D Kurzman, Darius Babusis, Adrian S Ray, Noel Sousa-Powers, Daniel B Tumas

Abstract

Multiple myeloma (MM) is an important human and canine cancer for which novel therapies remain necessary. VDC-1101 (formerly GS-9219), a novel double prodrug of the anti-proliferative nucleotide analog 9-(2-phosphonylmethoxyethyl) guanine (PMEG), possesses potent cytotoxic activity in vitro in human lymphoblasts and leukemia cell lines and in vivo in spontaneous canine lymphoma. Given the similarity in lineage between lymphoma and MM, we hypothesized that VDC-1101 would be active against MM.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Italy 1 1%
Unknown 89 98%

Demographic breakdown

Readers by professional status Count As %
Other 17 19%
Student > Postgraduate 15 16%
Researcher 14 15%
Student > Master 8 9%
Student > Ph. D. Student 5 5%
Other 11 12%
Unknown 21 23%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 37 41%
Medicine and Dentistry 19 21%
Biochemistry, Genetics and Molecular Biology 4 4%
Chemistry 3 3%
Environmental Science 1 1%
Other 4 4%
Unknown 23 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2019.
All research outputs
#3,415,510
of 25,374,917 outputs
Outputs from BMC Veterinary Research
#231
of 3,298 outputs
Outputs of similar age
#38,878
of 321,548 outputs
Outputs of similar age from BMC Veterinary Research
#6
of 58 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,298 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,548 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.