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Wnt3a: functions and implications in cancer

Overview of attention for article published in Cancer Communications, September 2015
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Title
Wnt3a: functions and implications in cancer
Published in
Cancer Communications, September 2015
DOI 10.1186/s40880-015-0052-4
Pubmed ID
Authors

Sha He, Yi Lu, Xia Liu, Xin Huang, Evan T. Keller, Chao-Nan Qian, Jian Zhang

Abstract

Wnt3a, one of Wnt family members, plays key roles in regulating pleiotropic cellular functions, including self-renewal, proliferation, differentiation, and motility. Accumulating evidence has suggested that Wnt3a promotes or suppresses tumor progression via the canonical Wnt signaling pathway depending on cancer type. In addition, the roles of Wnt3a signaling can be inhibited by multiple proteins or chemicals. Herein, we summarize the latest findings on Wnt3a as an important therapeutic target in cancer.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 134 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 134 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 30 22%
Student > Bachelor 27 20%
Student > Master 20 15%
Student > Doctoral Student 9 7%
Researcher 6 4%
Other 8 6%
Unknown 34 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 40 30%
Agricultural and Biological Sciences 21 16%
Medicine and Dentistry 17 13%
Pharmacology, Toxicology and Pharmaceutical Science 6 4%
Engineering 4 3%
Other 10 7%
Unknown 36 27%