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Characterization of a novel cell penetrating peptide derived from human Oct4

Overview of attention for article published in Cell Regeneration, January 2014
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1 tweeter

Citations

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Readers on

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67 Mendeley
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Title
Characterization of a novel cell penetrating peptide derived from human Oct4
Published in
Cell Regeneration, January 2014
DOI 10.1186/2045-9769-3-2
Pubmed ID
Authors

Eva Harreither, Hanna A Rydberg, Helene L Åmand, Vaibhav Jadhav, Lukas Fliedl, Christina Benda, Miguel A Esteban, Duanqing Pei, Nicole Borth, Regina Grillari-Voglauer, Oliver Hommerding, Frank Edenhofer, Bengt Nordén, Johannes Grillari

Abstract

Oct4 is a transcription factor that plays a major role for the preservation of the pluripotent state in embryonic stem cells as well as for efficient reprogramming of somatic cells to induced pluripotent stem cells (iPSC) or other progenitors. Protein-based reprogramming methods mainly rely on the addition of a fused cell penetrating peptide. This study describes that Oct4 inherently carries a protein transduction domain, which can translocate into human and mouse cells.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 1%
Uruguay 1 1%
Austria 1 1%
Japan 1 1%
United States 1 1%
Unknown 62 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 28%
Researcher 12 18%
Student > Master 9 13%
Professor > Associate Professor 6 9%
Student > Bachelor 5 7%
Other 13 19%
Unknown 3 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 33 49%
Biochemistry, Genetics and Molecular Biology 13 19%
Chemistry 5 7%
Medicine and Dentistry 4 6%
Neuroscience 2 3%
Other 5 7%
Unknown 5 7%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2014.
All research outputs
#10,681,152
of 12,044,660 outputs
Outputs from Cell Regeneration
#35
of 37 outputs
Outputs of similar age
#178,019
of 214,331 outputs
Outputs of similar age from Cell Regeneration
#10
of 10 outputs
Altmetric has tracked 12,044,660 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 37 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one scored the same or higher as 2 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 214,331 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one.