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Increased physical activity severely induces osteoarthritic changes in knee joints with papain induced sulfate-glycosaminoglycan depleted cartilage

Overview of attention for article published in Arthritis Research & Therapy, January 2014
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Citations

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Title
Increased physical activity severely induces osteoarthritic changes in knee joints with papain induced sulfate-glycosaminoglycan depleted cartilage
Published in
Arthritis Research & Therapy, January 2014
DOI 10.1186/ar4461
Pubmed ID
Authors

Michiel Siebelt, Harald C Groen, Stuart J Koelewijn, Erik de Blois, Marjan Sandker, Jan H Waarsing, Cristina Müller, Gerjo JVM van Osch, Marion de Jong, Harrie Weinans

Abstract

Articular cartilage needs sulphated-glycosaminoglycans (sGAG) to withstand high pressures while mechanically loaded. Chondrocyte sGAG synthesis is regulated by exposure to compressive forces. Moderate physical exercise is known to improve cartilage sGAG content and might protect against osteoarthritis (OA). This study investigated whether rat knee joints with sGAG depleted articular through papain injections might benefit from moderate exercise, or whether this increases the susceptibility for cartilage degeneration.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 75 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 18%
Student > Postgraduate 9 12%
Student > Master 9 12%
Student > Doctoral Student 7 9%
Student > Bachelor 7 9%
Other 15 20%
Unknown 15 20%
Readers by discipline Count As %
Medicine and Dentistry 20 26%
Engineering 11 14%
Agricultural and Biological Sciences 6 8%
Nursing and Health Professions 5 7%
Biochemistry, Genetics and Molecular Biology 3 4%
Other 12 16%
Unknown 19 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 February 2014.
All research outputs
#17,286,645
of 25,374,917 outputs
Outputs from Arthritis Research & Therapy
#2,536
of 3,380 outputs
Outputs of similar age
#203,962
of 323,393 outputs
Outputs of similar age from Arthritis Research & Therapy
#35
of 62 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,380 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,393 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.