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Vaccines for Invasive Fungal Infections

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Cover of 'Vaccines for Invasive Fungal Infections'

Table of Contents

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    Book Overview
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    Chapter 1 Mouse Immunization with Radioattenuated Yeast Cells of Paracoccidioides brasiliensis
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    Chapter 2 Heat-Killed Yeast as a Pan-Fungal Vaccine
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    Chapter 3 Immunoinformatics as a Tool for New Antifungal Vaccines
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    Chapter 4 Rational Design of T Lymphocyte Epitope-Based Vaccines Against Coccidioides Infection
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    Chapter 5 Identification of Fungal T Cell Epitopes by Mass Spectrometry-Based Proteomics
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    Chapter 6 Intranasal Antifungal Vaccination Using DNA-Transfected Dendritic Cells
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    Chapter 7 DNAhsp65 Vaccine as Therapy against Paracoccidioidomycosis
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    Chapter 8 Idiotypic Antifungal Vaccination: Immunoprotection by Antiidiotypic Antibiotic Antibodies
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    Chapter 9 Peptide Vaccine Against Paracoccidioidomycosis
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    Chapter 10 Methodology for Anti-Cryptococcal Vaccine Development
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    Chapter 11 Beta-Glucan Particles as Vaccine Adjuvant Carriers
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    Chapter 12 Th1-Inducing Agents in Prophylaxis and Therapy for Paracoccidioidomycosis
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    Chapter 13 Nanoparticle-Based Mycosis Vaccine
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    Chapter 14 Yeast Expressing Gp43 Protein as a Vaccine Against Paracoccidioides brasiliensis Infection
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    Chapter 15 Vaccination with Phage-Displayed Antigenic Epitope
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    Chapter 16 Preparation of an Oral Vaccine by Proteome Analysis and Molecular Display Technology
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    Chapter 17 Precise and Efficient In-Frame Integration of an Exogenous GFP Tag in Aspergillus fumigatus by a CRISPR System
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    Chapter 18 Endpoint Assessment in Rabbit Models of Invasive Pulmonary Aspergillosis and Mucormycosis
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    Chapter 19 CD4+ T Cells Mediate Aspergillosis Vaccine Protection
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    Chapter 20 T-Cell-Mediated Cross-Protective Immunity
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    Chapter 21 Assessment of Post-Vaccination Phagocytic Activation Using Candida albicans Killing Assays
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    Chapter 22 Immunization with Antigen-Pulsed Dendritic Cells Against Highly Virulent Cryptococcus gattii Infection: Analysis of Cytokine-Producing T Cells
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    Chapter 23 Testing Antifungal Vaccines in an Animal Model of Invasive Candidiasis and in Human Mucosal Candidiasis
Attention for Chapter 8: Idiotypic Antifungal Vaccination: Immunoprotection by Antiidiotypic Antibiotic Antibodies
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Chapter title
Idiotypic Antifungal Vaccination: Immunoprotection by Antiidiotypic Antibiotic Antibodies
Chapter number 8
Book title
Vaccines for Invasive Fungal Infections
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-7104-6_8
Pubmed ID
Book ISBNs
978-1-4939-7103-9, 978-1-4939-7104-6
Authors

Luciano Polonelli, Walter Magliani, Stefania Conti

Editors

Markus Kalkum, Margarita Semis

Abstract

As implied by the idiotypic network theory, the interaction between the functional epitope of a microbicidal molecule (X) and its specific cell-wall receptor (RX) on sensitive microorganisms may be imaged by the bond between the idiotype (Id) of a neutralizing monoclonal antibody (anti-X Ab) and its anti-idiotype (anti-Id) X-like Ab (anti-anti-X Ab). Consequently, anti-X Ab Id may mimic RX acting as a vaccine (idiotypic vaccination) for the elicitation of protective anti-Id Abs with antibiotic activity (antibiobodies).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Professor 1 25%
Student > Bachelor 1 25%
Unknown 2 50%
Readers by discipline Count As %
Medicine and Dentistry 2 50%
Unknown 2 50%