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Suppression of neuroinflammation in forebrain-specific Cdk5 conditional knockout mice by PPARγ agonist improves neuronal loss and early lethality

Overview of attention for article published in Journal of Neuroinflammation, February 2014
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Title
Suppression of neuroinflammation in forebrain-specific Cdk5 conditional knockout mice by PPARγ agonist improves neuronal loss and early lethality
Published in
Journal of Neuroinflammation, February 2014
DOI 10.1186/1742-2094-11-28
Pubmed ID
Authors

Elias Utreras, Ryusuke Hamada, Michaela Prochazkova, Anita Terse, Satoru Takahashi, Toshio Ohshima, Ashok B Kulkarni

Abstract

Cyclin-dependent kinase 5 (Cdk5) is essential for brain development and function, and its deregulated expression is implicated in some of neurodegenerative diseases. We reported earlier that the forebrain-specific Cdk5 conditional knockout (cKO) mice displayed an early lethality associated with neuroinflammation, increased expression of the neuronal tissue-type plasminogen activator (tPA), and neuronal migration defects.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 16%
Researcher 3 12%
Student > Bachelor 3 12%
Student > Ph. D. Student 3 12%
Professor 2 8%
Other 5 20%
Unknown 5 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 28%
Neuroscience 6 24%
Pharmacology, Toxicology and Pharmaceutical Science 2 8%
Nursing and Health Professions 1 4%
Unspecified 1 4%
Other 2 8%
Unknown 6 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2014.
All research outputs
#17,712,213
of 22,743,667 outputs
Outputs from Journal of Neuroinflammation
#1,930
of 2,617 outputs
Outputs of similar age
#220,737
of 307,217 outputs
Outputs of similar age from Journal of Neuroinflammation
#42
of 63 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,617 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,217 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.