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Five Unprecedented Secondary Metabolites from the Spider Parasitic Fungus Akanthomyces novoguineensis

Overview of attention for article published in Molecules, June 2017
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Title
Five Unprecedented Secondary Metabolites from the Spider Parasitic Fungus Akanthomyces novoguineensis
Published in
Molecules, June 2017
DOI 10.3390/molecules22060991
Pubmed ID
Authors

Soleiman E. Helaly, Wilawan Kuephadungphan, Souwalak Phongpaichit, Janet Jennifer Luangsa-ard, Vatcharin Rukachaisirikul, Marc Stadler

Abstract

Five new compounds including the glycosylated β-naphthol (1, akanthol), a glycosylated pyrazine (2, akanthozine), and three amide derivatives including a hydroxamic acid derivative (3-5) were isolated from the spider-associated fungus Akanthomyces novoguineensis (Cordycipitaceae, Ascomycota). Their structures were elucidated by using high resolution mass spectrometry (HRMS) and NMR spectroscopy. In this study, the antimicrobial, cytotoxic, anti-biofilm, and nematicidal activities of the new compounds were evaluated. The distribution pattern of secondary metabolites in the species was also revealed in which more isolates of A. novoguineensis were encountered and their secondary metabolite profiles were examined using analytical HPLC with diode array and mass spectrometric detection (HPLC-DAD/MS). Remarkably, all isolated compounds are specifically produced by A. novoguineensis.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 19%
Student > Bachelor 4 15%
Researcher 3 11%
Student > Doctoral Student 2 7%
Student > Postgraduate 2 7%
Other 6 22%
Unknown 5 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 41%
Biochemistry, Genetics and Molecular Biology 4 15%
Chemistry 4 15%
Business, Management and Accounting 1 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Other 0 0%
Unknown 6 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2017.
All research outputs
#22,867,974
of 25,498,750 outputs
Outputs from Molecules
#18,322
of 23,890 outputs
Outputs of similar age
#290,288
of 332,032 outputs
Outputs of similar age from Molecules
#299
of 349 outputs
Altmetric has tracked 25,498,750 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 23,890 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 349 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.