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Ketamine as antidepressant? Current state and future perspectives.

Overview of attention for article published in Current Neuropharmacology, January 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#37 of 621)
  • High Attention Score compared to outputs of the same age (95th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

news
2 news outlets
twitter
25 tweeters

Citations

dimensions_citation
21 Dimensions

Readers on

mendeley
122 Mendeley
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Title
Ketamine as antidepressant? Current state and future perspectives.
Published in
Current Neuropharmacology, January 2014
DOI 10.2174/1570159x113119990043
Pubmed ID
Authors

H W W Hasselmann, H. W.W. Hasselmann

Abstract

Major depressive disorder (MDD) is a serious mental disorder that ranks among the major causes of disease burden. Standard medical treatment targeting cerebral monoamines often provides only insufficient symptom relief and fails in approximately every fifth patient. The complexity of MDD therefore, reflects more than monoaminergic dysregulation. Initial research argues the case for excessive glutamate levels, suggesting that antiglutamatergic drugs might be useful in treating MDD. Ketamine is a non-selective, high-affinity N-methyl-D-aspartate receptor (NMDAR) antagonist most commonly used in pediatric and animal surgery. In the past, ketamine has gained popularity because of its ability to rapidly elevate mood, even in treatment-resistant and bipolar depression. However, there are still many obstacles before widespread clinical approval of ketamine treatment could become reality. In this review, ketamine's powerful antidepressant effects are discussed and further research necessary for therapeutic application is outlined. NMDAR antagonists provide an entirely new way of treating the manifold appearances of depression that should not be left unused.

Twitter Demographics

The data shown below were collected from the profiles of 25 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Germany 1 <1%
Unknown 120 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 31 25%
Student > Master 19 16%
Student > Ph. D. Student 16 13%
Researcher 12 10%
Student > Postgraduate 10 8%
Other 19 16%
Unknown 15 12%
Readers by discipline Count As %
Medicine and Dentistry 30 25%
Neuroscience 19 16%
Psychology 16 13%
Agricultural and Biological Sciences 15 12%
Pharmacology, Toxicology and Pharmaceutical Science 8 7%
Other 14 11%
Unknown 20 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 34. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 June 2018.
All research outputs
#679,775
of 16,527,462 outputs
Outputs from Current Neuropharmacology
#37
of 621 outputs
Outputs of similar age
#9,055
of 190,856 outputs
Outputs of similar age from Current Neuropharmacology
#4
of 11 outputs
Altmetric has tracked 16,527,462 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 621 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 190,856 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.