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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Effects of Tolvaptan in patients with acute heart failure: a systematic review and meta-analysis
|
|---|---|
| Published in |
BMC Cardiovascular Disorders, June 2017
|
| DOI | 10.1186/s12872-017-0598-y |
| Pubmed ID | |
| Authors |
Chunbin Wang, Bo Xiong, Lin Cai |
| Abstract |
Acute heart failure, which requires urgent evaluation and treatment, is a leading cause for admission to the emergency department. The aim of this meta-analysis was to evaluate the effects of tolvaptan on acute heart failure and compare them with the effects of conventional therapy or placebo. The electronic databases PubMed, EMBASE, and the Cochrane Controlled Trial registry were searched from their starting dates to October 24, 2016. Two authors independently read the trials and extracted related information from the included studies. We used fixed-effects or random-effects models to assess the overall combined risk estimates according to I(2) statistics. Analysis to determine sensitivity and publication bias was conducted. Six randomised controlled trials from eight articles, with a total of 746 patients, were included for analysis. Compared with the control, tolvaptan reduced body weight in two days (WMD 1.35; 95% CI 0.75 to 1.96), elevated sodium level in two days (WMD 2.33; 95% CI 1.08 to 3.57) and five days (WMD 1.57; 95% CI 0.04 to 3.09), and ameliorated symptoms of dyspnoea (RR 0.82; 95% CI 0.71-0.95). However, tolvaptan did not improve long-term (RR 1.04; 95% CI 0.66-1.62) or short-term all-cause mortality (RR 0.89; 95% CI 0.45-1.76), incidence of clinical events (worsening heart failure, RR 0.75; 95% CI 0.50-1.12 and worsening renal function, RR 0.97; 95% CI 0.75-1.27), and length of hospital stay in patients (WMD 0.14; 95% CI -0.29 to 2.38) with acute heart failure. Tolvaptan can decrease body weight, increase serum sodium level, and ameliorate some of the congestion symptoms in patients with acute heart failure, which may help avoid the overdose of loop diuretics, especially in patients with renal dysfunction. |
X Demographics
The data shown below were collected from the profiles of 31 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 7 | 23% |
| Mexico | 2 | 6% |
| United Kingdom | 1 | 3% |
| Colombia | 1 | 3% |
| Egypt | 1 | 3% |
| Unknown | 19 | 61% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 19 | 61% |
| Practitioners (doctors, other healthcare professionals) | 9 | 29% |
| Scientists | 3 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 65 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 8 | 12% |
| Researcher | 8 | 12% |
| Student > Master | 6 | 9% |
| Student > Doctoral Student | 5 | 8% |
| Student > Bachelor | 5 | 8% |
| Other | 13 | 20% |
| Unknown | 20 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 34% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 11% |
| Nursing and Health Professions | 5 | 8% |
| Biochemistry, Genetics and Molecular Biology | 3 | 5% |
| Computer Science | 2 | 3% |
| Other | 6 | 9% |
| Unknown | 20 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2023.
All research outputs
#1,932,957
of 25,463,724 outputs
Outputs from BMC Cardiovascular Disorders
#71
of 1,937 outputs
Outputs of similar age
#36,906
of 330,246 outputs
Outputs of similar age from BMC Cardiovascular Disorders
#5
of 53 outputs
Altmetric has tracked 25,463,724 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,937 research outputs from this source. They receive a mean Attention Score of 4.2. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,246 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.