Title |
Virulence difference between the prototypic Schu S4 strain (A1a) and Francisella tularensisA1a, A1b, A2 and type B strains in a murine model of infection
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Published in |
BMC Infectious Diseases, February 2014
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DOI | 10.1186/1471-2334-14-67 |
Pubmed ID | |
Authors |
Claudia R Molins, Mark J Delorey, Brook M Yockey, John W Young, John T Belisle, Martin E Schriefer, Jeannine M Petersen |
Abstract |
The use of prototypic strains is common among laboratories studying infectious agents as it promotes consistency for data comparability among and between laboratories. Schu S4 is the prototypic virulent strain of Francisella tularensis and has been used extensively as such over the past six decades. Studies have demonstrated virulence differences among the two clinically relevant subspecies of F. tularensis, tularensis (type A) and holarctica (type B) and more recently between type A subpopulations (A1a, A1b and A2). Schu S4 belongs to the most virulent subspecies of F. tularensis, subspecies tularensis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 3% |
Sweden | 1 | 3% |
Unknown | 28 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 8 | 27% |
Researcher | 6 | 20% |
Professor > Associate Professor | 4 | 13% |
Professor | 2 | 7% |
Student > Bachelor | 2 | 7% |
Other | 3 | 10% |
Unknown | 5 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Immunology and Microbiology | 9 | 30% |
Agricultural and Biological Sciences | 5 | 17% |
Veterinary Science and Veterinary Medicine | 3 | 10% |
Nursing and Health Professions | 2 | 7% |
Medicine and Dentistry | 2 | 7% |
Other | 2 | 7% |
Unknown | 7 | 23% |