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Mendeley readers
Chapter title |
Use of Reporter Genes to Analyze Estrogen Response: The Transgenic Zebrafish Model
|
---|---|
Chapter number | 24 |
Book title |
Estrogen Receptors
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Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3127-9_24 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3126-2, 978-1-4939-3127-9
|
Authors |
Daniel A. Gorelick, Caroline Lucia Pinto, Ruixin Hao, Maria Bondesson, Gorelick, Daniel A., Pinto, Caroline Lucia, Hao, Ruixin, Bondesson, Maria |
Abstract |
In vivo models to detect estrogenic compounds are very valuable for screening for endocrine disruptors. Here we describe the use of transgenic estrogen reporter zebrafish as an in vivo model for identification of estrogenic properties of compounds. Live imaging of these transgenic fish provides knowledge of estrogen receptor specificity of different ligands as well as dynamics of estrogen signaling. Coupled to image analysis, the model can provide quantitative dose-response information on estrogenic activity of chemical compounds. |
Mendeley readers
The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 9 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Doctoral Student | 2 | 22% |
Student > Bachelor | 2 | 22% |
Student > Ph. D. Student | 2 | 22% |
Student > Master | 1 | 11% |
Professor > Associate Professor | 1 | 11% |
Other | 0 | 0% |
Unknown | 1 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 3 | 33% |
Agricultural and Biological Sciences | 2 | 22% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 11% |
Computer Science | 1 | 11% |
Neuroscience | 1 | 11% |
Other | 0 | 0% |
Unknown | 1 | 11% |