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Unusual Lipid A from a cold adapted bacterium: detailed structural characterization

Overview of attention for article published in ChemBioChem, June 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (56th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

Mentioned by

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5 tweeters
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1 Facebook page

Readers on

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6 Mendeley
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Title
Unusual Lipid A from a cold adapted bacterium: detailed structural characterization
Published in
ChemBioChem, June 2017
DOI 10.1002/cbic.201700287
Pubmed ID
Authors

Corsaro, Maria Michela, Casillo, Angela, Ziaco, Marcello, Lindner, Buko, Parrilli, Ermenegilda, Schwudke, Dominik, Holgado, Aurora, Verstrepen, Lynn, Sannino, Filomena, Beyaert, Rudi, Lanzetta, Rosa, Tutino, Maria Luisa, Corsaro, Maria Michela, Tutino, Maria Luisa

Abstract

Colwellia psychrerythraea 34H is a Gram-negative cold-adapted microorganism that adopts many strategies to cope with the limitations due to the low temperatures of its habitat. In this study, we reported the complete characterization of the lipid A moiety from the lipopolysaccharide of Colwellia, to find out if structural features could be linked to the cold-adaptation strategy. The lipid A and its partially deacylated derivative were completely characterized by means of high resolution mass spectrometry, NMR spectroscopy, and chemical analysis. An unusual structure, consisting of 3-hydroxy unsaturated tetradecenoic acid as component of the primary acylation pattern, was identified. In addition, the presence of a partially acylated phosphoglycerol moiety on the secondary acylation site at 3-position of the reducing GlcN caused a tremendous natural heterogeneity of the lipid A structure. Biological activity assays indicated that Colwellia psychrerythraea 34H lipid A did not show any either agonistic or antagonistic effect when tested in human macrophages.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 33%
Professor 1 17%
Student > Bachelor 1 17%
Professor > Associate Professor 1 17%
Unspecified 1 17%
Other 0 0%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 50%
Chemistry 2 33%
Unspecified 1 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2017.
All research outputs
#3,744,886
of 8,583,850 outputs
Outputs from ChemBioChem
#471
of 2,127 outputs
Outputs of similar age
#101,485
of 243,184 outputs
Outputs of similar age from ChemBioChem
#25
of 76 outputs
Altmetric has tracked 8,583,850 research outputs across all sources so far. This one has received more attention than most of these and is in the 54th percentile.
So far Altmetric has tracked 2,127 research outputs from this source. They receive a mean Attention Score of 2.5. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,184 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.