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Early changes in cytokine expression in peste des petits ruminants disease

Overview of attention for article published in Veterinary Research, February 2014
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Mentioned by

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1 tweeter

Citations

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27 Dimensions

Readers on

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31 Mendeley
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Title
Early changes in cytokine expression in peste des petits ruminants disease
Published in
Veterinary Research, February 2014
DOI 10.1186/1297-9716-45-22
Pubmed ID
Abstract

Peste des petits ruminants is a viral disease of sheep and goats that has spread through most of Africa as well as the Middle East and the Indian subcontinent. Although, the spread of the disease and its economic impact has made it a focus of international concern, relatively little is known about the nature of the disease itself. We have studied the early stages of pathogenesis in goats infected with six different isolates of Peste des petits ruminants virus representing all four known lineages of the virus. No lineage-specific difference in the pathogenicity of the virus isolates was observed, although there was evidence that even small numbers of cell culture passages could affect the degree of pathogenicity of an isolate. A consistent reduction in CD4+ T cells was observed at 4 days post infection (dpi). Measurement of the expression of various cytokines showed elements of a classic inflammatory response but also a relatively early induction of interleukin 10, which may be contributing to the observed disease.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Algeria 1 3%
Kenya 1 3%
Unknown 29 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 29%
Researcher 6 19%
Student > Master 5 16%
Student > Doctoral Student 4 13%
Other 2 6%
Other 3 10%
Unknown 2 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 39%
Veterinary Science and Veterinary Medicine 7 23%
Biochemistry, Genetics and Molecular Biology 3 10%
Medicine and Dentistry 2 6%
Environmental Science 1 3%
Other 2 6%
Unknown 4 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 February 2014.
All research outputs
#3,061,134
of 4,507,509 outputs
Outputs from Veterinary Research
#300
of 417 outputs
Outputs of similar age
#74,083
of 110,329 outputs
Outputs of similar age from Veterinary Research
#19
of 26 outputs
Altmetric has tracked 4,507,509 research outputs across all sources so far. This one is in the 20th percentile – i.e., 20% of other outputs scored the same or lower than it.
So far Altmetric has tracked 417 research outputs from this source. They receive a mean Attention Score of 2.6. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
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We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.