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Left ventricular outflow tract velocity time integral outperforms ejection fraction and Doppler-derived cardiac output for predicting outcomes in a select advanced heart failure cohort

Overview of attention for article published in Cardiovascular Ultrasound, July 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#13 of 246)
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

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24 tweeters
facebook
1 Facebook page
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1 Google+ user

Citations

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6 Dimensions

Readers on

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37 Mendeley
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Title
Left ventricular outflow tract velocity time integral outperforms ejection fraction and Doppler-derived cardiac output for predicting outcomes in a select advanced heart failure cohort
Published in
Cardiovascular Ultrasound, July 2017
DOI 10.1186/s12947-017-0109-4
Pubmed ID
Authors

Christina Tan, David Rubenson, Ajay Srivastava, Rajeev Mohan, Michael R. Smith, Kristen Billick, Samuel Bardarian, J. Thomas Heywood, Christina Tan, David Rubenson, Ajay Srivastava, Rajeev Mohan, Michael R. Smith, Kristen Billick, Samuel Bardarian, J. Thomas Heywood

Abstract

Left ventricular outflow tract velocity time integral (LVOT VTI) is a measure of cardiac systolic function and cardiac output. Heart failure patients with low cardiac output are known to have poor cardiovascular outcomes. Thus, extremely low LVOT VTI may predict heart failure patients at highest risk for mortality. Patients with heart failure and extremely low LVOT VTI were identified from a single-center database. Baseline characteristics and heart failure related clinical outcomes (death, LVAD) were obtained at 12 months. Correlation between clinical endpoints and the following variables were analyzed: ejection fraction (EF), pulmonary artery systolic pressure (PASP), NYHA class, renal function, Doppler cardiac output (CO), and LVOT VTI. Study cohort consisted of 100 patients. At the 12-month follow up period, 30 events (28 deaths, 2 LVADs) were identified. Occurrence of death and LVAD implantation was statistically associated with a lower LVOT VTI (p = 0.039) but not EF (p = 0.169) or CO (p = 0.217). In multivariate analysis, LVOT VTI (p = 0.003) remained statistically significant, other significant variables were age (p = 0.033) and PASP (p = 0.022). Survival analysis by LVOT VTI tertile demonstrated an unadjusted hazard ratio of 4.755 (CI 1.576-14.348, p = 0.006) for combined LVAD and mortality at one year. Extremely low LVOT VTI strongly predicts adverse outcomes and identifies patients who may benefit most from advanced heart failure therapies.

Twitter Demographics

The data shown below were collected from the profiles of 24 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 22%
Unspecified 7 19%
Researcher 5 14%
Student > Postgraduate 4 11%
Student > Bachelor 4 11%
Other 9 24%
Readers by discipline Count As %
Medicine and Dentistry 20 54%
Unspecified 11 30%
Engineering 2 5%
Decision Sciences 1 3%
Neuroscience 1 3%
Other 2 5%

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 September 2018.
All research outputs
#1,072,620
of 13,457,774 outputs
Outputs from Cardiovascular Ultrasound
#13
of 246 outputs
Outputs of similar age
#34,886
of 263,388 outputs
Outputs of similar age from Cardiovascular Ultrasound
#2
of 6 outputs
Altmetric has tracked 13,457,774 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 246 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,388 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.