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MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity

Overview of attention for article published in Genome Biology (Online Edition), July 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)

Mentioned by

news
1 news outlet
twitter
12 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
54 Dimensions

Readers on

mendeley
106 Mendeley
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Title
MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity
Published in
Genome Biology (Online Edition), July 2017
DOI 10.1186/s13059-017-1261-8
Pubmed ID
Authors

David Latrasse, Teddy Jégu, Huchen Li, Axel de Zelicourt, Cécile Raynaud, Stéphanie Legras, Andrea Gust, Olga Samajova, Alaguraj Veluchamy, Naganand Rayapuram, Juan Sebastian Ramirez-Prado, Olga Kulikova, Jean Colcombet, Jean Bigeard, Baptiste Genot, Ton Bisseling, Moussa Benhamed, Heribert Hirt

Abstract

Microbial-associated molecular patterns activate several MAP kinases, which are major regulators of the innate immune response in Arabidopsis thaliana that induce large-scale changes in gene expression. Here, we determine whether microbial-associated molecular pattern-triggered gene expression involves modifications at the chromatin level. Histone acetylation and deacetylation are major regulators of microbial-associated molecular pattern-triggered gene expression and implicate the histone deacetylase HD2B in the reprogramming of defence gene expression and innate immunity. The MAP kinase MPK3 directly interacts with and phosphorylates HD2B, thereby regulating the intra-nuclear compartmentalization and function of the histone deacetylase. By studying a number of gene loci that undergo microbial-associated molecular pattern-dependent activation or repression, our data reveal a mechanistic model for how protein kinase signaling directly impacts chromatin reprogramming in plant defense.

Twitter Demographics

The data shown below were collected from the profiles of 12 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 106 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 106 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 29%
Researcher 27 25%
Student > Bachelor 9 8%
Student > Master 9 8%
Professor > Associate Professor 6 6%
Other 9 8%
Unknown 15 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 61 58%
Biochemistry, Genetics and Molecular Biology 24 23%
Business, Management and Accounting 1 <1%
Pharmacology, Toxicology and Pharmaceutical Science 1 <1%
Earth and Planetary Sciences 1 <1%
Other 1 <1%
Unknown 17 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 December 2017.
All research outputs
#1,335,267
of 16,650,161 outputs
Outputs from Genome Biology (Online Edition)
#1,325
of 3,510 outputs
Outputs of similar age
#33,721
of 270,406 outputs
Outputs of similar age from Genome Biology (Online Edition)
#1
of 1 outputs
Altmetric has tracked 16,650,161 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,510 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.2. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 270,406 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them