Chapter title |
Methods for Microencapsulated Porcine Islet Production
|
---|---|
Chapter number | 26 |
Book title |
Cell Microencapsulation
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-6364-5_26 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6362-1, 978-1-4939-6364-5
|
Authors |
Masayuki Shimoda, Shinichi Matsumoto M.D., Ph.D., Shinichi Matsumoto |
Editors |
Emmanuel C. Opara |
Abstract |
Allogeneic islet transplantation has become a viable option for the treatment of unstable type 1 diabetes; however, donor shortage and the necessity for immunosuppressive drugs are two major drawbacks of this treatment. Microencapsulated porcine islets can solve both of these drawbacks, and clinical trials have been conducted. Previous clinical trials demonstrated the safety and marginal efficacy of this treatment; therefore, it is necessary to improve its efficacy. The production of microencapsulated porcine islets consists of pancreas procurement, islet isolation, and microencapsulation. In this chapter, we describe our current methods for porcine pancreas procurement, islet isolation, and microencapsulation. |
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Geographical breakdown
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Unknown | 7 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 2 | 29% |
Professor | 2 | 29% |
Student > Doctoral Student | 1 | 14% |
Unknown | 2 | 29% |
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Medicine and Dentistry | 3 | 43% |
Agricultural and Biological Sciences | 2 | 29% |
Unknown | 2 | 29% |