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Cell Microencapsulation

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Cover of 'Cell Microencapsulation'

Table of Contents

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    Book Overview
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    Chapter 1 Cell Microencapsulation
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    Chapter 2 Applications of Cell Microencapsulation
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    Chapter 3 Cell Microencapsulation: Dripping Methods
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    Chapter 4 Field Effect Microparticle Generation for Cell Microencapsulation
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    Chapter 5 Microfluidic Approach to Cell Microencapsulation
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    Chapter 6 Polymeric Materials for Cell Microencapsulation
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    Chapter 7 Polymeric Materials for Perm-Selective Coating of Alginate Microbeads
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    Chapter 8 Determination of the Mechanical Strength of Microcapsules
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    Chapter 9 The Diffusive Properties of Hydrogel Microcapsules for Cell Encapsulation
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    Chapter 10 Methods for Incorporating Oxygen-Generating Biomaterials into Cell Culture and Microcapsule Systems
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    Chapter 11 Noninvasive Tracking of Alginate-Microencapsulated Cells
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    Chapter 12 Retrieval of Microencapsulated Islet Grafts for Post-transplant Evaluation
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    Chapter 13 A Method of Porcine Pancreatic Islet Isolation for Microencapsulation
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    Chapter 14 Selective Osmotic Shock (SOS)-Based Islet Isolation for Microencapsulation
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    Chapter 15 Preparation and Characterization of Alginate–Chitosan Microcapsule for Hepatocyte Culture
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    Chapter 16 Use of Flow Focusing Technique for Microencapsulation of Myoblasts
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    Chapter 17 Alginate Microbeads for Cell and Protein Delivery
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    Chapter 18 Compartmentalization of Two Cell Types in Multilayered Alginate Microcapsules
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    Chapter 19 Primary Choroid Plexus Tissue for Use in Cellular Therapy
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    Chapter 20 Cell Microencapsulation
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    Chapter 21 Microencapsulated Cells for Cancer Therapy
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    Chapter 22 Microencapsulation of Bacterial Cells by Emulsion Technique for Probiotic Application
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    Chapter 23 Microencapsulation of Islets for the Treatment of Type 1 Diabetes Mellitus (T1D)
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    Chapter 24 Cell Microencapsulation
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    Chapter 25 Microencapsulation in Clinical Islet Xenotransplantation
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    Chapter 26 Methods for Microencapsulated Porcine Islet Production
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    Chapter 27 Microencapsulation of Parathyroid Cells for the Treatment of Hypoparathyroidism
Attention for Chapter 27: Microencapsulation of Parathyroid Cells for the Treatment of Hypoparathyroidism
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Chapter title
Microencapsulation of Parathyroid Cells for the Treatment of Hypoparathyroidism
Chapter number 27
Book title
Cell Microencapsulation
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6364-5_27
Pubmed ID
Book ISBNs
978-1-4939-6362-1, 978-1-4939-6364-5
Authors

Patricio Cabané Toledo M.D., Ph.D., F.A.C.S., Ricardo L. Rossi, Pablo Caviedes M.D., Ph.D., Patricio Cabané Toledo, Pablo Caviedes

Editors

Emmanuel C. Opara

Abstract

Cell encapsulation is an alternative to avoid rejection of grafted tissue, thus bringing an interesting alternative in cell therapy. It is particularly relevant in ailments where only the implant of small quantities of tissues is warranted. In such circumstances, the use of immunosuppressive therapy in patients implanted with tissues from donors is debatable, yet unavoidable at present in order to prevent rejection and/or sensitization of the host to the tissue, in turn jeopardizing the success of successive implants. Hence, a new line of thought, which aims to provide an immunoprivileged site for the grafted tissue, while at the same time insure its nutrition, as well as its survival and continued function, appears as a most attractive possibility. To achieve these goals, cells or tissues harvested for transplant could be encapsulated in biologically compatible matrices. Among the matrices currently in existence, sodium alginate is the most widely used polymer for tissue encapsulation.In the present chapter, we present a technique used to encapsulate parathyroid tissue, for use as cell transplant therapy in patients with secondary hypoparathyroidism. With this procedure, implanted tissue survives and remains functional for up to 18 months.

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 25%
Researcher 1 13%
Student > Ph. D. Student 1 13%
Other 1 13%
Student > Master 1 13%
Other 0 0%
Unknown 2 25%
Readers by discipline Count As %
Medicine and Dentistry 3 38%
Biochemistry, Genetics and Molecular Biology 2 25%
Pharmacology, Toxicology and Pharmaceutical Science 1 13%
Unknown 2 25%