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Mendeley readers
Attention Score in Context
| Title |
Making heads or tails of mitochondrial membranes in longevity and aging: a role for comparative studies
|
|---|---|
| Published in |
Longevity & Healthspan, March 2014
|
| DOI | 10.1186/2046-2395-3-3 |
| Pubmed ID | |
| Authors |
Teresa G Valencak, Vian Azzu |
| Abstract |
Mitochondria play vital roles in metabolic energy transduction, intermediate molecule metabolism, metal ion homeostasis, programmed cell death and regulation of the production of reactive oxygen species. As a result of their broad range of functions, mitochondria have been strongly implicated in aging and longevity. Numerous studies show that aging and decreased lifespan are also associated with high reactive oxygen species production by mitochondria, increased mitochondrial DNA and protein damage, and with changes in the fatty acid composition of mitochondrial membranes. It is possible that the extent of fatty acid unsaturation of the mitochondrial membrane determines susceptibility to lipid oxidative damage and downstream protein and genome toxicity, thereby acting as a determinant of aging and lifespan. Reviewing the vast number of comparative studies on mitochondrial membrane composition, metabolism and lifespan reveals some evidence that lipid unsaturation ratios may correlate with lifespan. However, we caution against simply relating these two traits. They may be correlative but have no functional relation. We discuss an important methodology for body mass and phylogenetic correction in comparative studies. |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 3% |
| United States | 1 | 2% |
| Romania | 1 | 2% |
| Unknown | 55 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 25% |
| Researcher | 9 | 15% |
| Professor > Associate Professor | 5 | 8% |
| Student > Doctoral Student | 5 | 8% |
| Professor | 4 | 7% |
| Other | 16 | 27% |
| Unknown | 5 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 36% |
| Biochemistry, Genetics and Molecular Biology | 20 | 34% |
| Veterinary Science and Veterinary Medicine | 3 | 5% |
| Medicine and Dentistry | 2 | 3% |
| Chemistry | 2 | 3% |
| Other | 6 | 10% |
| Unknown | 5 | 8% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2014.
All research outputs
#3,535,450
of 22,747,498 outputs
Outputs from Longevity & Healthspan
#15
of 26 outputs
Outputs of similar age
#35,821
of 221,907 outputs
Outputs of similar age from Longevity & Healthspan
#2
of 3 outputs
Altmetric has tracked 22,747,498 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 26 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.0. This one scored the same or higher as 11 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 221,907 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.