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A role for PPARα in the medial prefrontal cortex in formalin-evoked nociceptive responding in rats

Overview of attention for article published in British Journal of Pharmacology, March 2014
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1 tweeter

Citations

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Title
A role for PPARα in the medial prefrontal cortex in formalin-evoked nociceptive responding in rats
Published in
British Journal of Pharmacology, March 2014
DOI 10.1111/bph.12540
Pubmed ID
Authors

B N Okine, K Rea, W M Olango, J Price, S Herdman, M K Madasu, M Roche, D P Finn

Abstract

The nuclear hormone receptor, PPARα, and its endogenous ligands, are involved in pain modulation. PPARα is expressed in the medial prefrontal cortex (mPFC), a key brain region involved in both the cognitive-affective component of pain and in descending modulation of pain. However, the role of PPARα in the mPFC in pain responding has not been investigated. Here, we investigated the effects of pharmacological modulation of PPARα in the rat mPFC on formalin-evoked nociceptive behaviour and the impact of formalin-induced nociception on components of PPARα signalling in the mPFC.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 30 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 23%
Other 3 10%
Researcher 3 10%
Student > Postgraduate 3 10%
Professor 2 6%
Other 8 26%
Unknown 5 16%
Readers by discipline Count As %
Neuroscience 8 26%
Medicine and Dentistry 5 16%
Agricultural and Biological Sciences 4 13%
Veterinary Science and Veterinary Medicine 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Other 3 10%
Unknown 7 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 March 2014.
All research outputs
#9,944,427
of 12,421,956 outputs
Outputs from British Journal of Pharmacology
#4,927
of 5,516 outputs
Outputs of similar age
#128,830
of 189,988 outputs
Outputs of similar age from British Journal of Pharmacology
#83
of 110 outputs
Altmetric has tracked 12,421,956 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,516 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 189,988 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.