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Vaccines against Allergies

Overview of attention for book
Attention for Chapter 143: Passive Immunization with Allergen-Specific Antibodies.
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1 tweeter

Citations

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1 Dimensions

Readers on

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15 Mendeley
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Chapter title
Passive Immunization with Allergen-Specific Antibodies.
Chapter number 143
Book title
Vaccines against Allergies
Published in
Current topics in microbiology and immunology, June 2011
DOI 10.1007/82_2011_143
Pubmed ID
Book ISBNs
978-3-64-220053-3, 978-3-64-220054-0
Authors

Sabine Flicker, Elisabeth Gadermaier, Christoph Madritsch, Rudolf Valenta

Abstract

The induction of allergen-specific IgG antibodies has been identified as a major mechanism responsible for the reduction of allergic inflammation in allergic patients treated by allergen-specific immunotherapy. Several studies suggest that allergen-specific IgG antibodies induced by vaccination with allergens block mast cell and basophil degranulation, IgE-facilitated allergen presentation to T cells and IgE production. The availability of recombinant allergens and technologies for the production of recombinant human antibodies allows engineering of allergen-specific antibodies which can be used for passive immunization (i.e., therapy) and eventually for the prevention of allergy (i.e., prophylaxis). This chapter summarizes data supporting the possible use of allergen-specific antibodies for treatment and prophylaxis. Finally, concrete approaches for the treatment and prevention of allergy based on blocking antibodies are envisioned.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 33%
Student > Postgraduate 2 13%
Other 2 13%
Student > Ph. D. Student 2 13%
Student > Master 2 13%
Other 1 7%
Unknown 1 7%
Readers by discipline Count As %
Medicine and Dentistry 10 67%
Biochemistry, Genetics and Molecular Biology 1 7%
Agricultural and Biological Sciences 1 7%
Arts and Humanities 1 7%
Unknown 2 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 June 2011.
All research outputs
#3,557,853
of 5,039,474 outputs
Outputs from Current topics in microbiology and immunology
#248
of 351 outputs
Outputs of similar age
#2,917,542
of 4,032,068 outputs
Outputs of similar age from Current topics in microbiology and immunology
#237
of 338 outputs
Altmetric has tracked 5,039,474 research outputs across all sources so far. This one is in the 16th percentile – i.e., 16% of other outputs scored the same or lower than it.
So far Altmetric has tracked 351 research outputs from this source. They receive a mean Attention Score of 2.2. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 4,032,068 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 338 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.