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Bioinformatics prediction of overlapping frameshifted translation products in mammalian transcripts

Overview of attention for article published in BMC Genomics, March 2008
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Citations

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Title
Bioinformatics prediction of overlapping frameshifted translation products in mammalian transcripts
Published in
BMC Genomics, March 2008
DOI 10.1186/1471-2164-9-122
Pubmed ID
Authors

Sebastien Ribrioux, Adrian Brüngger, Birgit Baumgarten, Klaus Seuwen, Markus R John

Abstract

Exceptionally, a single nucleotide sequence can be translated in vivo in two different frames to yield distinct proteins. In the case of the G-protein alpha subunit XL-alpha-s transcript, a frameshifted open reading frame (ORF) in exon 1 is translated to yield a structurally distinct protein called Alex, which plays a role in platelet aggregation and neurological processes. We carried out a novel bioinformatics screen for other possible dual-frame translated sequences, based on comparative genomics.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 4%
Spain 1 2%
Unknown 48 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 22%
Student > Master 10 20%
Student > Ph. D. Student 9 18%
Professor > Associate Professor 4 8%
Student > Postgraduate 3 6%
Other 7 14%
Unknown 7 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 35%
Biochemistry, Genetics and Molecular Biology 16 31%
Medicine and Dentistry 3 6%
Mathematics 2 4%
Computer Science 2 4%
Other 3 6%
Unknown 7 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2008.
All research outputs
#22,759,452
of 25,373,627 outputs
Outputs from BMC Genomics
#9,840
of 11,244 outputs
Outputs of similar age
#92,288
of 95,742 outputs
Outputs of similar age from BMC Genomics
#42
of 42 outputs
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So far Altmetric has tracked 11,244 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,742 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.