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Autoinflammatory bone disorders with special focus on chronic recurrent multifocal osteomyelitis (CRMO)

Overview of attention for article published in Pediatric Rheumatology, December 2013
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  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

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3 X users
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1 Facebook page

Citations

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157 Dimensions

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108 Mendeley
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Title
Autoinflammatory bone disorders with special focus on chronic recurrent multifocal osteomyelitis (CRMO)
Published in
Pediatric Rheumatology, December 2013
DOI 10.1186/1546-0096-11-47
Pubmed ID
Authors

Christian M Hedrich, Sigrun R Hofmann, Jessica Pablik, Henner Morbach, Hermann J Girschick

Abstract

Sterile bone inflammation is the hallmark of autoinflammatory bone disorders, including chronic nonbacterial osteomyelitis (CNO) with its most severe form chronic recurrent multifocal osteomyelitis (CRMO). Autoinflammatory osteopathies are the result of a dysregulated innate immune system, resulting in immune cell infiltration of the bone and subsequent osteoclast differentiation and activation. Interestingly, autoinflammatory bone disorders are associated with inflammation of the skin and/or the intestine. In several monogenic autoinflammatory bone disorders mutations in disease-causing genes have been reported. However, regardless of recent developments, the molecular pathogenesis of CNO/CRMO remains unclear.Here, we discuss the clinical presentation and molecular pathophysiology of human autoinflammatory osteopathies and animal models with special focus on CNO/CRMO. Treatment options in monogenic autoinflammatory bone disorders and CRMO will be illustrated.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 3%
Spain 2 2%
Canada 1 <1%
Egypt 1 <1%
Unknown 101 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 15%
Other 14 13%
Student > Doctoral Student 14 13%
Student > Postgraduate 12 11%
Student > Ph. D. Student 11 10%
Other 25 23%
Unknown 16 15%
Readers by discipline Count As %
Medicine and Dentistry 72 67%
Immunology and Microbiology 4 4%
Agricultural and Biological Sciences 4 4%
Biochemistry, Genetics and Molecular Biology 3 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 <1%
Other 4 4%
Unknown 20 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2018.
All research outputs
#13,911,941
of 22,749,166 outputs
Outputs from Pediatric Rheumatology
#388
of 693 outputs
Outputs of similar age
#171,893
of 306,717 outputs
Outputs of similar age from Pediatric Rheumatology
#7
of 18 outputs
Altmetric has tracked 22,749,166 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 693 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,717 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.