Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein

Overview of attention for article published in Bioorganic & Medicinal Chemistry Letters, February 2014

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patent: 14 patents

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Fragments vs MCL-1, again and again

Practical Fragments, 24 Mar 2014

Last year we highlighted a paper from Stephen Fesik’s group at Vanderbilt in which he used SAR by NMR and fragment merging to…

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