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Quantitative assessment of the diagnostic role of APC promoter methylation in non-small cell lung cancer

Overview of attention for article published in Clinical Epigenetics, March 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)

Mentioned by

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8 X users

Citations

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28 Dimensions

Readers on

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32 Mendeley
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Title
Quantitative assessment of the diagnostic role of APC promoter methylation in non-small cell lung cancer
Published in
Clinical Epigenetics, March 2014
DOI 10.1186/1868-7083-6-5
Pubmed ID
Authors

Shicheng Guo, Lixing Tan, Weilin Pu, Junjie Wu, Kuan Xu, Jinhui Wu, Qiang Li, Yanyun Ma, Jibin Xu, Li Jin, Jiucun Wang

Abstract

Adenomatous polyposis coli (APC) has been reported to be a candidate tumor suppressor in many cancers. However, the diagnostic role of APC promoter methylation in non-small cell lung cancer (NSCLC) remains unclear. We systematically integrated published articles and DNA methylation microarray data to investigate the diagnostic performance of the APC methylation test for NSCLC. Two thousand two hundred and fifty-nine NSCLC tumor samples and 1,039 controls were collected from 17 published studies and TCGA NSCLC data. The association between APC promoter methylation and NSCLC was evaluated in a meta-analysis. An independent DNA methylation microarray dataset from TCGA project, in which five CpG sites located in the promoter region of APC were involved, was used to validate the results of the meta-analysis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 3%
United States 1 3%
Unknown 30 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 16%
Researcher 5 16%
Student > Master 4 13%
Student > Bachelor 3 9%
Professor > Associate Professor 3 9%
Other 7 22%
Unknown 5 16%
Readers by discipline Count As %
Medicine and Dentistry 10 31%
Biochemistry, Genetics and Molecular Biology 8 25%
Agricultural and Biological Sciences 2 6%
Computer Science 1 3%
Sports and Recreations 1 3%
Other 3 9%
Unknown 7 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2014.
All research outputs
#6,192,595
of 22,749,166 outputs
Outputs from Clinical Epigenetics
#402
of 1,241 outputs
Outputs of similar age
#59,063
of 223,836 outputs
Outputs of similar age from Clinical Epigenetics
#1
of 4 outputs
Altmetric has tracked 22,749,166 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 1,241 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 223,836 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them