Chapter title |
The Enteric Nervous System
|
---|---|
Chapter number | 13 |
Book title |
The Enteric Nervous System
|
Published in |
Advances in experimental medicine and biology, July 2016
|
DOI | 10.1007/978-3-319-27592-5_13 |
Pubmed ID | |
Book ISBNs |
978-3-31-927590-1, 978-3-31-927592-5
|
Authors |
Foong, Jaime Pei Pei, Jaime Pei Pei Foong |
Abstract |
Owing to over three decades of research, we now have a good understanding of the genetic and molecular control of enteric nervous system (ENS) development during embryonic and prenatal stages. On the other hand, it has only just become clear that a substantial process of ENS maturation occurs after birth (Hao et al. 2013a). During postnatal stages, in addition to genetic influences, ENS development is also potentially affected by the external environment. Thus it is possible that manipulating certain environmental factors could help prevent or reduce motility disorders. However the genetic and environmental factors that regulate postnatal ENS development remain unknown. Researchers have used a variety of animal models that are easy to manipulate genetically or experimentally, and have short gestational periods, to understand the development of the ENS. Notably, due to the availability of mouse models for several human enteric neuropathies, many studies have used the mature and developing murine ENS as a model. Here, I will discuss recent advances in knowledge about postnatal development of the murine ENS, and highlight future directions for this emerging research field. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 3 | 23% |
Researcher | 3 | 23% |
Student > Doctoral Student | 1 | 8% |
Lecturer > Senior Lecturer | 1 | 8% |
Student > Postgraduate | 1 | 8% |
Other | 0 | 0% |
Unknown | 4 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 3 | 23% |
Neuroscience | 3 | 23% |
Medicine and Dentistry | 2 | 15% |
Biochemistry, Genetics and Molecular Biology | 1 | 8% |
Unknown | 4 | 31% |