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Optimisation of an immunohistochemistry method for the determination of androgen receptor expression levels in circulating tumour cells

Overview of attention for article published in BMC Cancer, March 2014
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Title
Optimisation of an immunohistochemistry method for the determination of androgen receptor expression levels in circulating tumour cells
Published in
BMC Cancer, March 2014
DOI 10.1186/1471-2407-14-226
Pubmed ID
Authors

Jeffrey Cummings, Robert Sloane, Karen Morris, Cong Zhou, Matt Lancashire, David Moore, Tony Elliot, Noel Clarke, Caroline Dive

Abstract

AZD3514 inhibits and down regulates the androgen receptor (AR) and has undergone clinical trials in prostate cancer. To provide proof-of-mechanism (POM) in patients, an immunohistochemistry (IHC) method for determination of AR in circulating tumour cells (CTC) was developed and validated.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
India 1 2%
France 1 2%
Unknown 52 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 18%
Student > Ph. D. Student 8 15%
Student > Bachelor 5 9%
Other 4 7%
Lecturer 3 5%
Other 12 22%
Unknown 13 24%
Readers by discipline Count As %
Medicine and Dentistry 11 20%
Biochemistry, Genetics and Molecular Biology 8 15%
Agricultural and Biological Sciences 6 11%
Nursing and Health Professions 2 4%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 9 16%
Unknown 17 31%