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Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury

Overview of attention for article published in Journal of Neuroinflammation, March 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

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10 X users
facebook
1 Facebook page
video
1 YouTube creator

Citations

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296 Dimensions

Readers on

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150 Mendeley
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Title
Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury
Published in
Journal of Neuroinflammation, March 2014
DOI 10.1186/1742-2094-11-59
Pubmed ID
Authors

Hai-tao Zhu, Chen Bian, Ji-chao Yuan, Wei-hua Chu, Xin Xiang, Fei Chen, Cheng-shi Wang, Hua Feng, Jiang-kai Lin

Abstract

Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that contributes to substantial neuronal damage and behavioral impairment, and Toll-like receptor 4 (TLR4) is an important mediator of thiscascade. In the current study, we tested the hypothesis that curcumin, a phytochemical compound with potent anti-inflammatory properties that is extracted from the rhizome Curcuma longa, alleviates acute inflammatory injury mediated by TLR4 following TBI.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 150 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
United Kingdom 1 <1%
Unknown 147 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 17%
Student > Master 22 15%
Student > Bachelor 21 14%
Researcher 13 9%
Student > Doctoral Student 11 7%
Other 26 17%
Unknown 32 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 21 14%
Medicine and Dentistry 21 14%
Agricultural and Biological Sciences 20 13%
Neuroscience 19 13%
Pharmacology, Toxicology and Pharmaceutical Science 14 9%
Other 18 12%
Unknown 37 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 July 2015.
All research outputs
#5,387,458
of 22,749,166 outputs
Outputs from Journal of Neuroinflammation
#979
of 2,617 outputs
Outputs of similar age
#50,402
of 224,538 outputs
Outputs of similar age from Journal of Neuroinflammation
#4
of 28 outputs
Altmetric has tracked 22,749,166 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,617 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 224,538 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.