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LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3

Overview of attention for article published in BMC Biology, March 2014
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Title
LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3
Published in
BMC Biology, March 2014
DOI 10.1186/1741-7007-12-25
Pubmed ID
Authors

Yushan Li, Jirong Pan, Chao Wei, Juan Chen, Ying Liu, Jiali Liu, Xiaoxin Zhang, Sylvia M Evans, Yan Cui, Sheng Cui

Abstract

Abnormalities in pyloric development or in contractile function of the pylorus cause reflux of duodenal contents into the stomach and increase the risk of gastric metaplasia and cancer. Abnormalities of the pyloric region are also linked to congenital defects such as the relatively common neonatal hypertrophic pyloric stenosis, and primary duodenogastric reflux. Therefore, understanding pyloric development is of great clinical relevance. Here, we investigated the role of the LIM homeodomain transcription factor Isl1 in pyloric development.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
Unknown 20 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 29%
Student > Ph. D. Student 3 14%
Student > Master 3 14%
Professor > Associate Professor 3 14%
Student > Bachelor 2 10%
Other 2 10%
Unknown 2 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 38%
Biochemistry, Genetics and Molecular Biology 7 33%
Medicine and Dentistry 2 10%
Immunology and Microbiology 1 5%
Nursing and Health Professions 1 5%
Other 0 0%
Unknown 2 10%