NMR fragment screening
CureFFI.org,
what is fragment screening? Over the past few years I’ve done a lot of thinking about high-throughput screening as a starting…
The Right Kinase, Part II – Roche and Daiichi’s Vemurafenib Approved
The Haystack,
Last week, the FDA approved Zelboraf (vemurafenib), co-marketed by Roche and Daiichi Sankyo, for the treatment of melanoma…
First fragment-based drug approved
Practical Fragments,
Today marks history with the first FDA approval of a drug to come out of fragment-based screening. The drug is branded as…
Melanoma sequencing identifies new druggable targets
Free Association,
Next-generation sequencing technologies are enabling unbiased searches for new cancer genes at an unprecedented scale. In 2011…