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Prediction of Protein Secondary Structure

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Cover of 'Prediction of Protein Secondary Structure'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Where the Name “GOR” Originates: A Story
  3. Altmetric Badge
    Chapter 2 The GOR Method of Protein Secondary Structure Prediction and Its Application as a Protein Aggregation Prediction Tool
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    Chapter 3 Consensus Prediction of Charged Single Alpha-Helices with CSAHserver
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    Chapter 4 Predicting Protein Secondary Structure Using Consensus Data Mining (CDM) Based on Empirical Statistics and Evolutionary Information
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    Chapter 5 Accurate Prediction of One-Dimensional Protein Structure Features Using SPINE-X
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    Chapter 6 SPIDER2: A Package to Predict Secondary Structure, Accessible Surface Area, and Main-Chain Torsional Angles by Deep Neural Networks
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    Chapter 7 Backbone Dihedral Angle Prediction
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    Chapter 8 One-Dimensional Structural Properties of Proteins in the Coarse-Grained CABS Model
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    Chapter 9 Assessing Predicted Contacts for Building Protein Three-Dimensional Models
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    Chapter 10 Fast and Accurate Accessible Surface Area Prediction Without a Sequence Profile
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    Chapter 11 How to Predict Disorder in a Protein of Interest
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    Chapter 12 Intrinsic Disorder and Semi-disorder Prediction by SPINE-D
  14. Altmetric Badge
    Chapter 13 Prediction of Protein Secondary Structure
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    Chapter 14 Prediction of Disordered RNA, DNA, and Protein Binding Regions Using DisoRDPbind
  16. Altmetric Badge
    Chapter 15 Prediction of Protein Secondary Structure
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    Chapter 16 Computational Approaches for Predicting Binding Partners, Interface Residues, and Binding Affinity of Protein–Protein Complexes
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    Chapter 17 In Silico Prediction of Linear B-Cell Epitopes on Proteins
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    Chapter 18 Prediction of Protein Phosphorylation Sites by Integrating Secondary Structure Information and Other One-Dimensional Structural Properties
  20. Altmetric Badge
    Chapter 19 Predicting Post-Translational Modifications from Local Sequence Fragments Using Machine Learning Algorithms: Overview and Best Practices
  21. Altmetric Badge
    Chapter 20 CX, DPX, and PCW: Web Servers for the Visualization of Interior and Protruding Regions of Protein Structures in 3D and 1D
  22. Altmetric Badge
    Chapter 21 Erratum to: One-Dimensional Structural Properties of Proteins in the Coarse-Grained CABS Model
Attention for Chapter 17: In Silico Prediction of Linear B-Cell Epitopes on Proteins
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Chapter title
In Silico Prediction of Linear B-Cell Epitopes on Proteins
Chapter number 17
Book title
Prediction of Protein Secondary Structure
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6406-2_17
Pubmed ID
Book ISBNs
978-1-4939-6404-8, 978-1-4939-6406-2
Authors

Yasser EL-Manzalawy, Drena Dobbs, Vasant G. Honavar, EL-Manzalawy, Yasser, Dobbs, Drena, Honavar, Vasant G.

Abstract

Antibody-protein interactions play a critical role in the humoral immune response. B-cells secrete antibodies, which bind antigens (e.g., cell surface proteins of pathogens). The specific parts of antigens that are recognized by antibodies are called B-cell epitopes. These epitopes can be linear, corresponding to a contiguous amino acid sequence fragment of an antigen, or conformational, in which residues critical for recognition may not be contiguous in the primary sequence, but are in close proximity within the folded protein 3D structure.Identification of B-cell epitopes in target antigens is one of the key steps in epitope-driven subunit vaccine design, immunodiagnostic tests, and antibody production. In silico bioinformatics techniques offer a promising and cost-effective approach for identifying potential B-cell epitopes in a target vaccine candidate. In this chapter, we show how to utilize online B-cell epitope prediction tools to identify linear B-cell epitopes from the primary amino acid sequence of proteins.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 72 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 13%
Researcher 9 13%
Student > Bachelor 9 13%
Student > Master 4 6%
Student > Doctoral Student 3 4%
Other 11 15%
Unknown 27 38%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 18%
Agricultural and Biological Sciences 8 11%
Immunology and Microbiology 8 11%
Engineering 3 4%
Nursing and Health Professions 2 3%
Other 9 13%
Unknown 29 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 September 2023.
All research outputs
#20,395,752
of 25,068,002 outputs
Outputs from Methods in molecular biology
#8,846
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Outputs of similar age
#324,560
of 432,282 outputs
Outputs of similar age from Methods in molecular biology
#704
of 1,084 outputs
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