Title |
Cadmium induces lung inflammation independent of lung cell proliferation: a molecular approach
|
---|---|
Published in |
Journal of Inflammation, June 2009
|
DOI | 10.1186/1476-9255-6-19 |
Pubmed ID | |
Authors |
Subhadip Kundu, Suman Sengupta, Soumya Chatterjee, Soham Mitra, Arindam Bhattacharyya |
Abstract |
Cadmium is one of the inflammation-related xenobiotics and has been regarded as a potent carcinogen. The relationship between inflammation and cell proliferation due to chronic infection has been studied, but the mechanism is not fully clear. Though the mode of cadmium toxicity is well characterized in animal cells, still it requires some further investigations. Previously we reported that cadmium induces immune cell death in Swiss albino mice. In the present study we showed that instead of inducing cell death mechanism, cadmium in low concentration triggers proliferation in mice lung cell and our results reveals that prior to the induction of proliferation it causes severe inflammation. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 2 | 4% |
India | 1 | 2% |
United Kingdom | 1 | 2% |
Canada | 1 | 2% |
United States | 1 | 2% |
Poland | 1 | 2% |
Unknown | 49 | 88% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 18% |
Student > Master | 6 | 11% |
Student > Bachelor | 6 | 11% |
Researcher | 5 | 9% |
Lecturer | 4 | 7% |
Other | 12 | 21% |
Unknown | 13 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 17 | 30% |
Medicine and Dentistry | 10 | 18% |
Environmental Science | 4 | 7% |
Biochemistry, Genetics and Molecular Biology | 4 | 7% |
Unspecified | 2 | 4% |
Other | 5 | 9% |
Unknown | 14 | 25% |