Title |
Infection and genotype remodel the entire soybean transcriptome
|
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Published in |
BMC Genomics, January 2009
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DOI | 10.1186/1471-2164-10-49 |
Pubmed ID | |
Authors |
Lecong Zhou, Santiago X Mideros, Lei Bao, Regina Hanlon, Felipe D Arredondo, Sucheta Tripathy, Konstantinos Krampis, Adam Jerauld, Clive Evans, Steven K St Martin, MA Saghai Maroof, Ina Hoeschele, Anne E Dorrance, Brett M Tyler |
Abstract |
High throughput methods, such as high density oligonucleotide microarray measurements of mRNA levels, are popular and critical to genome scale analysis and systems biology. However understanding the results of these analyses and in particular understanding the very wide range of levels of transcriptional changes observed is still a significant challenge. Many researchers still use an arbitrary cut off such as two-fold in order to identify changes that may be biologically significant. We have used a very large-scale microarray experiment involving 72 biological replicates to analyze the response of soybean plants to infection by the pathogen Phytophthora sojae and to analyze transcriptional modulation as a result of genotypic variation. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 2 | 4% |
Italy | 1 | 2% |
Brazil | 1 | 2% |
Australia | 1 | 2% |
Singapore | 1 | 2% |
United Kingdom | 1 | 2% |
Unknown | 50 | 88% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 20 | 35% |
Student > Ph. D. Student | 9 | 16% |
Student > Master | 9 | 16% |
Professor > Associate Professor | 7 | 12% |
Student > Bachelor | 3 | 5% |
Other | 6 | 11% |
Unknown | 3 | 5% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 44 | 77% |
Biochemistry, Genetics and Molecular Biology | 4 | 7% |
Computer Science | 2 | 4% |
Engineering | 2 | 4% |
Physics and Astronomy | 1 | 2% |
Other | 1 | 2% |
Unknown | 3 | 5% |