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X Demographics
Mendeley readers
Attention Score in Context
Title |
Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres
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Published in |
Acta Neuropathologica Communications, March 2014
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DOI | 10.1186/2051-5960-2-31 |
Pubmed ID | |
Authors |
Dacheng Ding, Kah Suan Lim, Charles G Eberhart |
Abstract |
Notch and Hedgehog signaling have been implicated in the pathogenesis and stem-like characteristics of glioblastomas, and inhibitors of the pathways have been suggested as new therapies for these aggressive tumors. It has also been reported that targeting both pathways simultaneously can be advantageous in treating glioblastoma neurospheres, but this is difficult to achieve in vivo using multiple agents. Since arsenic trioxide has been shown to inhibit both Notch and Hedgehog in some solid tumors, we examined its effects on these pathways and on stem cell phenotype in glioblastoma. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Unknown | 48 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 12 | 24% |
Researcher | 9 | 18% |
Student > Ph. D. Student | 8 | 16% |
Student > Doctoral Student | 3 | 6% |
Professor | 2 | 4% |
Other | 6 | 12% |
Unknown | 9 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 14 | 29% |
Medicine and Dentistry | 8 | 16% |
Biochemistry, Genetics and Molecular Biology | 5 | 10% |
Nursing and Health Professions | 1 | 2% |
Computer Science | 1 | 2% |
Other | 5 | 10% |
Unknown | 15 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2014.
All research outputs
#14,193,746
of 22,751,628 outputs
Outputs from Acta Neuropathologica Communications
#1,070
of 1,369 outputs
Outputs of similar age
#119,429
of 226,157 outputs
Outputs of similar age from Acta Neuropathologica Communications
#16
of 28 outputs
Altmetric has tracked 22,751,628 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,369 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.8. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,157 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.